Premature Ejaculation Wipes: How They Work & More

Mike Bohl, MD, MPH, ALM

Reviewed by Mike Bohl, MD

Written by Grace Gallagher

Published 08/29/2021

Updated 01/18/2024

You already know a moist towelette is the answer to mess-free chicken wings, but could a little prepackaged wipe also be the secret to helping you last longer in bed?

Well, friends, yes. Enter: premature ejaculation wipes. These single-use cloths desensitize the penis to help prevent premature ejaculation (PE).

Here, we’ll talk about premature ejaculation wipes and how they work to help prevent PE, plus potential side effects to be aware of (spoiler alert: not many). We’ll also go over other PE treatments if you’re not a wet-wipe guy.

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The idea of numbing your penis might make you shudder — but PE wipes don’t totally numb you. Instead, they desensitize the penis and glans (that’s the formal name for the rounded tip) so you don’t feel everything as acutely and, as a result, last longer.

The wipes use benzocaine as a numbing agent (the same topical anesthetic in Orajel). Other brands or PE sprays may contain a mix of benzocaine and lidocaine.

Like the little towelettes that come with your hot wings order, our Clockstopper benzocaine wipes are portable, wrapped in discreet packaging, pre-portioned and easy to use.

Premature ejaculation wipes are hassle-free and portable. If you keep a condom in your wallet, you can tuck a wipe packet next to it or stash them discreetly in your nightstand.

Choose your chew

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To use a delay wipe, unwrap it from the disposable sleeve. Avoid touching the wipe with your bare hands — it’s totally safe but might make your fingers numb. If you accidentally get some on your hands, no biggie. Just wash thoroughly with soap and warm water.

You can experiment with applying different amounts to different areas (starting with a swipe on the tip) to figure out what works best.

If you want more desensitization, apply the wipe to the shaft. Let it dry for five minutes before vaginal, anal or oral sex.

You may want to try one before masturbation first to get a good idea of how it’ll work during sex.

It might seem almost too good to be true that something as humble as a wet wipe is effective against premature ejaculation.

But science is on the side of premature ejaculation wipes. A small study of 21 men experiencing PE showed a statistically significant increase in the time it took to ejaculate when using desensitizing wipes before sex. The effects were even more notable after two months of use (so keep at it, even if you’re not sure initially).

Intravaginal ejaculatory latency time (IELT or IVELT) is just a math term for the time it takes to ejaculate during vaginal sex (yes, there’s sex math). Some data suggests that men with an IELT of less than a minute definitely have PE, while men with IELTs between one and one and a half minutes have “probable” PE.

The first study we mentioned found that in month one of use, the mean IELT was about 1.8 minutes for the placebo group and 2.75 minutes for those receiving treatment. After two months of use, the treatment group climbed to five and a half minutes.

The same study also found “no transference” to partners, meaning no numb vaginas. Win.

If you’re a parent of a small child, you might have heard that, as of 2018, the FDA (U.S. Food & Drug Administration) no longer allows over-the-counter baby teething gels containing benzocaine to be marketed or sold.

These products were banned because benzocaine is associated with a rare but serious blood condition known as methemoglobinemia, where the blood doesn’t carry enough oxygen. Understandably, this could make you wonder if benzocaine is safe — and if you want to put it on your private areas.

Rest assured that benzocaine gels, liquids and lozenges are FDA-approved for adults and considered safe when used as directed — though sprays aren’t specifically approved.

There are potential topical benzocaine side effects, however. These include:

  • Skin tenderness or redness

  • Skin rash and itchy, burning or stinging skin

  • Dry, white flakes where the medication was applied

  • Edema (swelling caused by excess fluid)

  • Excessive numbing, which makes sex difficult

Not to sound like a drug commercial, but if you or your partner experience side effects or an allergic reaction to benzocaine (which may look like swelling on the face, tongue, throat or lips, difficulty breathing or hives), speak to a healthcare provider or seek medical advice immediately.

There’s significant scientific research showing that benzocaine wipes are an effective tool for treating premature ejaculation. Still, alternative treatments abound, including some other treatments you can use in tandem with the wipe.

Topical PE Treatments

Other topical treatments for PE are available if you’re not keen on the idea of moist towelette. These include desensitizing sprays, creams and local anesthetics with other active ingredients.

Our Delay Spray and premature ejaculation wipes do have one notable difference, though. The spray uses lidocaine as a desensitizing agent, whereas — as you know by now — the wipes contain benzocaine.

To use the spray, apply three to ten spritzes (it’s a choose-your-own-adventure situation!) on your penis 10 to 15 minutes before sex.

Some research shows that lidocaine transfers to your partner if you’re not using a condom, which is a good reason to make sure you’ve waited enough time — or to try a different kind of treatment.

PE Medications

There’s currently no FDA-approved oral prescription drug for premature ejaculation. But that doesn’t mean you can’t take medication to delay ejaculation.

Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants sometimes prescribed off-label for the treatment of premature ejaculation. PDE5 inhibitors, which are used for ED, may also be used off label to treat PE.

Here’s what to know:

  • SSRI for PE. A 2007 randomized controlled trial looked at the effects of three SSRIs (fluoxetine, paroxetine and escitalopram) in 100 men with PE. All participants reported improvement in PE, and all medications were well tolerated. However, a double-blind 2019 study found that paroxetine (another SSRI) provided better efficacy than a placebo, fluoxetine and escitalopram in the treatment of premature ejaculation.

  • PDE5 inhibitors for PE. The PDE5 inhibitor sildenafil (guys, it’s Viagra®) is approved to treat erectile dysfunction (ED) in males ages 18 years and older, but it’s often prescribed off-label to help with climax control. A 2007 study on 180 men experiencing PE found that sildenafil was effective and safe in treating PE, with a higher efficacy than paroxetine.

PE Techniques

Not ready to take matters out of your own hands? Some home remedies for PE may help you control ejaculation. Learn about popular ejaculation-delaying methods below.

  • Stop-start method. The stop-start technique is what it sounds like. Right before you’re about to orgasm, stop having sex and then start again when the urge to ejaculate goes away — easier said than done, but worth a shot. According to experts, you should repeat the stop-start technique several times during sex.

  • Squeeze technique. Another option for delaying ejaculation without using desensitizing agents is the squeeze technique. Just before orgasm, pull out and gently squeeze the tip of your penis for about 30 seconds to decrease arousal. You may need to repeat the squeeze maneuver several times before returning to sex. The most obvious limitation of this technique is that it requires the self-control to stop, pull out and squeeze your penis.

  • Pelvic contraction during sex. Studies also show that performing the squeeze technique without manual pressure can be effective. Basically, you remain inside your partner but stop the motion of sex and contract the pelvic floor (think of a male kegel). A 2014 study concluded that pelvic floor exercises are a promising remedy for managing premature ejaculation.

  • Masturbation before intercourse. If There’s Something About Mary taught us anything, it’s that masturbation before a date is common (and that semen looks a whole lot like hair gel). Ben Stiller may have been onto something because research shows that masturbation prior to sex can delay ejaculation. Researchers suggest waiting roughly an hour post-masturbation before attempting sexual activity with a partner.


We don’t need to tell you exercise is good for you. But beyond keeping your heart healthy and your mood up, working out may be associated with a lower instance of PE.

One study compared people who engaged in regular physical activity to those who led a mostly sedentary lifestyle. More research is needed, but the findings were promising: PE was less frequent in men who exercised than those who lacked movement in their daily lives.


Premature ejaculation isn’t all in your head, by any means. Having said that, the condition can have both physiological and psychological components.

For instance, maybe your self-esteem has taken a hit, which makes you less interested in sex. Or perhaps performance anxiety is holding you back from getting intimate. And some men may overdo it on alcohol, hoping it’ll “diminish their sexual excitement” and allow them to last longer.

Regardless, having what you perceive as a sexual dysfunction can bring up anxiety and low self-esteem. Therapy, with or without your partner, can help.

More research is needed on the topic, as most studies examining the link between psychotherapy and PE are lacking in some way (no control group or a small sample size, for example).

However, the research that exists suggests that a combination of therapy and medication is a promising intervention for PE (and better than drugs alone).

delay spray for men

longer sex is yours for the taking

There’s much to like about premature ejaculation wipes — they’re easy to use, they’re portable and they work. 

Here are a few things to remember about the management of premature ejaculation when deciding if PE wipes are the best solution for you.

  • PE is divided into two subtypes: lifelong and acquired. Lifelong means it’s happened since your first sexual encounter, and acquired PE (as the name suggests) develops after a period of “normal” ejaculation time. Either way, premature ejaculation treatments (yep, like PE wipes) can help. 

  • PE wipes aren’t your only option. Not about the wipes? We won’t take it personally. Other options for premature ejaculation include oral medication, lidocaine spray, talk therapy or a combination of approaches.

  • There could be something else at play. Like many common conditions, PE could potentially be a sign of a more significant medical issue. That’s why it’s best to be seen by a healthcare professional.

If nothing else, ongoing premature ejaculation issues can be damaging to your sex life, with some men avoiding sexual activities to prevent embarrassment. For this reason, it’s always a good idea to seek medical attention.

Not a fan of in-person appointments? You can connect with a healthcare provider online through our platform to discuss premature ejaculation treatments.

To learn more about treatment options for PE, check out our guides to paroxetine for PE and surgery options for PE.

12 Sources

Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references.

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  2. Myers, C., & Smith, M. (2019). Pelvic floor muscle training improves erectile dysfunction and premature ejaculation: a systematic review. Physiotherapy, 105(2), 235–243.
  3. Oleary M. P. (2004). Managing early ejaculation: what does the future hold?. Reviews in urology, 6(1), 5–10.
  4. Publishing, H. (n.d.). Kegels: Not for women only. Retrieved March 29, 2021, from
  5. [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Premature ejaculation: What can I do on my own? 2019 Sep 12. Available from:
  6. McMahon C. G. (2007). Premature ejaculation. Indian journal of urology : IJU : journal of the Urological Society of India, 23(2), 97–108.
  7. Hyun J. S. (2017). AB012. Update on treatments for premature ejaculation. Translational Andrology and Urology, 6(Suppl 3), AB012.
  8. Mohee, A., & Eardley, I. (2011). Medical therapy for premature ejaculation. Therapeutic advances in urology, 3(5), 211–222.
  9. Ridwan Shabsigh, Michael A. Perelman, Robert H. Getzenberg, Allison Grant, Jed Kaminetsky. RANDOMIZED, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY, SAFETY, AND TOLERABILITY OF BENZOCAINE WIPES IN SUBJECTS WITH PREMATURE EJACULATION. Journal of Mens Health. 2019. 15(3);80-88.
  10. Shabsigh, R., Ridwan Shabsigh More articles by this author, Kaminetsky, J., Jed Kaminetsky More articles by this author, Yang, M., Michael Yang More articles by this author, Perelman, M., Michael Perelman (n.d.). PD69-02 double-blind, randomized controlled trial of TOPICAL 4% BENZOCAINE wipes for management of PREMATURE Ejaculation: Interim analysis. The Journal of Urology.
  11. Singh R, Al Khalili Y. Benzocaine. [Updated 2020 Nov 20]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from:
  12. Hersh, E. V., Ciancio, S. G., Kuperstein, A. S., Stoopler, E. T., Moore, P. A., Boynes, S. G., Levine, S. C., Casamassimo, P., Leyva, R., Mathew, T., Shibly, O., Creighton, P., Jeffers, G. E., Corby, P. M., Turetzky, S. N., Papas, A., Wallen, J., Idzik-Starr, C., & Gordon, S. M. (2013). An evaluation of 10 percent and 20 percent benzocaine gels in patients with acute toothaches: efficacy, tolerability and compliance with label dose administration directions. Journal of the American Dental Association (1939), 144(5), 517–526.
Editorial Standards

Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.

Mike Bohl, MD

Dr. Mike Bohl is a licensed physician, a Medical Advisor at Hims & Hers, and the Director of Scientific & Medical Content at a stealth biotech startup, where he is involved in pharmaceutical drug development. Prior to joining Hims & Hers, Dr. Bohl spent several years working in digital health, focusing on patient education. He has also worked in medical journalism for The Dr. Oz Show (receiving recognition for contributions from the National Academy of Television Arts and Sciences when the show won Outstanding Informative Talk Show at the 2016–2017 Daytime Emmy® Awards) and at Sharecare. He is a Medical Expert Board Member at Eat This, Not That! and a Board Member at International Veterinary Outreach.

Dr. Bohl obtained his Bachelor of Arts and Doctor of Medicine from Brown University, his Master of Public Health from Columbia University, and his Master of Liberal Arts in Extension Studies—Journalism from Harvard University. He is currently pursuing a Master of Business Administration and Master of Science in Healthcare Leadership at Cornell University. Dr. Bohl trained in internal medicine with a focus on community health at NYU Langone Health.

Dr. Bohl is Certified in Public Health by the National Board of Public Health Examiners, Medical Writer Certified by the American Medical Writers Association, a certified Editor in the Life Sciences by the Board of Editors in the Life Sciences, a Certified Personal Trainer and Certified Nutrition Coach by the National Academy of Sports Medicine, and a Board Certified Medical Affairs Specialist by the Accreditation Council for Medical Affairs. He has graduate certificates in Digital Storytelling and Marketing Management & Digital Strategy from Harvard Extension School and certificates in Business Law and Corporate Governance from Cornell Law School.

In addition to his written work, Dr. Bohl has experience creating medical segments for radio and producing patient education videos. He has also spent time conducting orthopedic and biomaterial research at Case Western Reserve University and University Hospitals of Cleveland and practicing clinically as a general practitioner on international medical aid projects with Medical Ministry International.

Dr. Bohl lives in Manhattan and enjoys biking, resistance training, sailing, scuba diving, skiing, tennis, and traveling. You can find Dr. Bohl on LinkedIn for more information.


  • Younesi, M., Knapik, D. M., Cumsky, J., Donmez, B. O., He, P., Islam, A., Learn, G., McClellan, P., Bohl, M., Gillespie, R. J., & Akkus, O. (2017). Effects of PDGF-BB delivery from heparinized collagen sutures on the healing of lacerated chicken flexor tendon in vivo. Acta biomaterialia, 63, 200–209.

  • Gebhart, J. J., Weinberg, D. S., Bohl, M. S., & Liu, R. W. (2016). Relationship between pelvic incidence and osteoarthritis of the hip. Bone & joint research, 5(2), 66–72.

  • Gebhart, J. J., Bohl, M. S., Weinberg, D. S., Cooperman, D. R., & Liu, R. W. (2015). Pelvic Incidence and Acetabular Version in Slipped Capital Femoral Epiphysis. Journal of pediatric orthopedics, 35(6), 565–570.

  • Islam, A., Bohl, M. S., Tsai, A. G., Younesi, M., Gillespie, R., & Akkus, O. (2015). Biomechanical evaluation of a novel suturing scheme for grafting load-bearing collagen scaffolds for rotator cuff repair. Clinical biomechanics (Bristol, Avon), 30(7), 669–675.

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