Content
New: A 2-in-1 pill for sex + testosterone support
Ads for male enhancement supplements are everywhere. If you turn off your pop-up blocker for even a second, you’ll be bombarded with spots for “the best sex pills for men,“ “the best penis enlargement pills,“ or the “best male enhancement pills.“
The products often tout ridiculous claims about being able to grow your penis several inches giving you the sexual stamina of a wildebeest. And they can look tempting. But be warned: There currently aren’t any FDA-approved male enhancement pills on the market. Literally none.
But there are other options.
Below, we’ll discuss some concerns around non-prescription male enhancement pills and supplements, from lack of efficacy data to hidden, potentially harmful ingredients. We’ll also go over how you can use FDA-approved medications to treat sex-related issues like erectile dysfunction (ED) to have more satisfying sex.
Content
Some of the most popular male enhancement pills are marketed as magic capsules that can cure any sex-related issue.
They say they can do things like:
Strengthen sex drive (libido)
Increase sexual satisfaction
Stimulate healthy blood flow (crucial for erections)
These male sexual enhancement pills are often promoted as the solution to all your sexual worries, whether you’re concerned about your penis size, your erections, or your general ability to please your partner.
But they aren’t really legit.
These so-called penis enhancement pills aren’t held to the same standards as FDA-approved medications. This means the manufacturers can try to make all sorts of vague claims.
Technically, they’re classified as dietary supplements. Many claim that natural ingredients like horny goat weed, ginseng, maca root, or ashwagandha can boost sexual performance, increase sexual desire, and reverse low libido. But again, this is far from the truth.
Worse yet, investigations have found that some of these products — including the famous Rhino pill brand — contain hidden ingredients that are potentially dangerous.
Currently, there aren’t any “male enhancement“ or “sexual enhancement“ pills approved by the U.S. Food and Drug Administration (FDA).
One thing to keep in mind about these pills is that, as herbal products and dietary supplements, they aren’t regulated in the same way as over-the-counter or prescription medications.
So something claiming to be the “best male enhancement pill” doesn’t need to go through the FDA’s strict approval process, evading multiple phases of clinical trials. Unlike FDA-approved medications, these products aren’t required to be tested for safety or effectiveness.
As you can imagine, this creates a lot of space for disingenuous business practices and less-than-truthful advertising.
Unscrupulous business practices are so commonplace in the non-prescription male enhancement pill market that the FDA actually maintains a list of tainted sexual enhancement products.
This list includes hundreds — literally hundreds — of entries, all for non-prescription male enhancement supplements containing potentially harmful substances.
The FDA has investigated numerous male enhancement pills available in gas stations, sex stores, and online marketplaces. It found that some non-prescription male enhancement products contain hidden ingredients.
That’s concerning, sure. But there’s more.
The FDA’s investigations also found that some of the products contain illegal amounts of legitimate pharmaceutical drugs and unlabeled stimulants.
It’s one thing to consume a little too much caffeine every once in a while. But it’s another thing entirely to take an unprescribed, underregulated, and unknown dose of, say, sildenafil or tadalafil.
These are the main ingredients in Viagra® and Cialis®, respectively, and they’ve both been found in non-prescription male performance boosters.
For example, a 2018 study assessed 353 adulterated sexual enhancement products identified by the FDA. Of these, 81 percent contained sildenafil and 20 percent contained tadalafil.
While that may sound like you’re getting more bang for your buck, remember: A big reason ED medications are available by prescription only is that dosages should be tailored to the patient’s individual needs.
Plus, pharmaceutical-grade medications are required to be made in pharmaceutical-quality laboratories. Let’s just say “enhancement“ pills don’t have nearly the same rigorous and regulated manufacturing quality standards.
So, yeah. Probably best to err on the side of caution here.
Just because non-prescription male enhancement pills probably aren’t worth the risk doesn’t mean you don’t have options. In fact, you have plenty.
ED medications are prescription drugs designed specifically to treat sexual health conditions like erectile dysfunction. They’ve also gone through a rigorous FDA testing and approval process, making them safe to use (for most people) when properly prescribed.
These include PDE5 inhibitors (that’s phosphodiesterase type 5 inhibitors). This type of drug works by relaxing blood vessels, thereby increasing blood flow to the penis, making it easier to get and maintain an erection when sexually aroused.
FDA-approved oral ED treatments include:
Sildenafil (the active ingredient in Viagra®)
Vardenafil (the active ingredient in Levitra®)
Avanafil (the active ingredient in Stendra®)
Keep scrolling for details about each prescription drug.
"The impact of the medication on my life has been profound. Not only did it address my physical symptoms, but it also boosted my confidence and improved my relationship with my partner. It felt like rediscovering a part of myself that I thought was lost.
"The journey wasn't just about treating ED; it was about reclaiming my well-being and happiness."
- Zachary, 39
Incentivized Review
Sildenafil citrate (or just sildenafil for short) is the generic form of Viagra. This widely used medication for ED has been approved by the FDA since the late 1990s.
You can take sildenafil 30 minutes to four hours before sex. A single dose can start working within 30 minutes.
In clinical trials performed as part of the drug’s FDA approval process, more than 80 percent of men reported improvements in erectile function at the highest dose (100 milligrams of sildenafil).
Even at lower sildenafil dosages of 25 and 50 milligrams, 63 and 74 percent of men with erectile dysfunction, respectively, reported improvements.
This makes sildenafil a great pill to use if you’re concerned about losing your erection during sex.
Sildenafil is generally a safe and effective medication. However, as with all medications, it does come with potential side effects. Your healthcare provider will go over these with you when they prescribe sildenafil.
Tadalafil is a long-lasting ED medication that can deliver relief from erectile dysfunction for up to 36 hours per dose. That’s why it’s sometimes referred to as “the weekend pill.“
Tadalafil is sold as a generic medication and under the brand name Cialis in several different strengths.
Because of its longer half-life, you might prefer tadalafil to other ED medications if you like to have sex more than once a day or don’t want to have to time your medication around the possibility of sexual activity. It’s very much a “set it and forget it“ type of medication.
Daily tadalafil prescribed at a reduced dose can provide ongoing relief from ED symptoms. Most other ED meds are taken as needed.
Tadalafil works in the same way as sildenafil and produces similar side effects. You can learn more about the side effects of tadalafil in our blog.
Next up is vardenafil, which is sold under the brand name Levitra. A single dose starts working in one hour. Some studies on vardenafil have found that it can remain effective for up to eight hours — which actually gives it a slight advantage over sildenafil.
As with taking any new prescription drug, it’s important to let your healthcare provider know about any medications you currently use or have recently used before considering vardenafil.
Available as Stendra, avanafil is the newest FDA-approved ED med on the market.
It’s more selective than other ED medications, meaning it more specifically targets the enzyme responsible for controlling blood flow to the penis. This means that Stendra has a lower risk of causing certain side effects compared to medications like sildenafil, tadalafil, and vardenafil.
It also gets to work faster. A single dose of avanafil produces improvements in erections in as little as 15 to 30 minutes in some men. So, if things are going better than you anticipated and your partner wants to head straight back to your place, you don’t have to hit the panic button.
Like other ED medications, avanafil can still cause adverse effects and interact with other drugs. So discuss this with your healthcare provider before you start treatment.
PDE5 inhibitors can interact with certain medications, including nitrates used to treat angina or high blood pressure (hypertension). They can also interact with nitrites, found in recreational “poppers.“ That’s why it’s crucial to speak to a healthcare professional before you start using them.
There are some other treatments for ED that the FDA has looked kindly upon. Alprostadil is an FDA-approved injectable medication for ED. And Eroxon is a recently FDA-authorized topical gel for ED you can buy without a prescription.
Hate to break it to you, gents, but there currently aren’t any dietary supplements or sexual enhancement pills that increase the size of your package. In fact, there aren’t any FDA-approved pills that’ll do it, either.
As discussed in our guide to penis growth pills, increasing your penis length or girth with a pill just isn’t possible. Not yet, anyway.
That said, there are alternatives to consider like:
But even then, these methods are either unproven, temporary, negligible, or alarmingly expensive.
Do male enhancement pills work, and if so, what are the best male enhancement pills? The answer is no — at least, not to the degree that they promise on their labels. And some of them are outright dangerous.
When it comes to non-prescription male enhancement pills, here’s the key info you should take away:
Since non-prescription male enhancement pills are considered dietary supplements, they’re not regulated by the FDA in the same way prescription medications are. This means they’re not required to undergo the same rigorous efficacy and safety testing.
These products sometimes contain hidden ingredients. The FDA actually maintains a public database of all the confirmed ones with unlisted ingredients.
There are proven, safer alternatives. If you’re not happy with your performance in the bedroom or are experiencing erectile dysfunction, you’ve got several FDA-approved options, including sildenafil, tadalafil, vardenafil, and avanafil.
If you’re interested in improving your erections, lasting longer in bed, or just ramping up your sex life, you’ll get far better results by consulting your healthcare provider than relying on male enhancement products.
Want to find out more before you start? Our guide to erectile dysfunction goes into detail about treatment options for ED and improved sexual function.
You can also look into premature ejaculation (PE) treatment if you’re having trouble finishing too soon.
Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!
This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.
Dr. Kelly Brown is a board certified Urologist and fellowship trained in Andrology. She is an accomplished men’s health expert with a robust background in healthcare innovation, clinical medicine, and academic research. Dr. Brown was previously Medical Director of a male fertility startup where she lead strategy and design of their digital health platform, an innovative education and telehealth model for delivering expert male fertility care.
She completed her undergraduate studies at University of North Carolina at Chapel Hill (go Heels!) with a Bachelor of Science in Radiologic Science and a Minor in Chemistry. She took a position at University of California Los Angeles as a radiologic technologist in the department of Interventional Cardiology, further solidifying her passion for medicine. She also pursued the unique opportunity to lead departmental design and operational development at the Ronald Reagan UCLA Medical Center, sparking her passion for the business of healthcare.
Dr. Brown then went on to obtain her doctorate in medicine from the prestigious Northwestern University - Feinberg School of Medicine and Masters in Business Administration from Northwestern University - Kellogg School of Management, with a concentration in Healthcare Management. During her surgical residency in Urology at University of California San Francisco, she utilized her research year to focus on innovations in telemedicine and then served as chief resident with significant contributions to clinical quality improvement. Dr. Brown then completed her Andrology Fellowship at Medical College of Wisconsin, furthering her expertise in male fertility, microsurgery, and sexual function.
Her dedication to caring for patients with compassion, understanding, as well as a unique ability to make guys instantly comfortable discussing anything from sex to sperm makes her a renowned clinician. In addition, her passion for innovation in healthcare combined with her business acumen makes her a formidable leader in the field of men’s health.
Dr. Brown is an avid adventurer; summiting Mount Kilimanjaro in Tanzania (twice!) and hiking the incredible Torres del Paine Trek in Patagonia, Chile. She deeply appreciates new challenges and diverse cultures on her travels. She lives in Denver with her husband, two children, and beloved Bernese Mountain Dog. You can find Dr. Brown on LinkedIn for more information.
Education & Training
Andrology Fellowship, Medical College of Wisconsin
Urology Residency, University of California San Francisco
M.D. Northwestern University Feinberg School of MedicineB.S. in Radiologic Science, Chemistry Minor, University of North Carolina at Chapel Hill
Published as Kelly Walker
Cowan, B, Walker, K., Rodgers, K., Agyemang, J. (2023). Hormonal Management Improves Semen Analysis Parameters in Men with Abnormal Concentration, Motility, and/or Morphology. Fertility and Sterility, Volume 118, Issue 5, e4. https://www.sciencedirect.com/journal/fertility-and-sterility/vol/120/issue/1/suppl/S
Walker, K., Gogoj, A., Honig, S., Sandlow, J. (2021). What’s New in Male Contraception? AUA Update Series, Volume 40. https://auau.auanet.org/content/update-series-2021-lesson-27-what%E2%80%99s-new-male-contraception
Walker, K., Shindel, A. (2019). AUA Erectile Dysfunction Guideline. AUA Update Series, Volume 38. https://auau.auanet.org/content/course-307
Walker, K., Ramstein, J., & Smith, J. (2019). Regret Regarding Fertility Preservation Decisions Among Male Cancer Patients. The Journal of Urology, 201(Supplement 4), e680-e681. https://www.auajournals.org/doi/10.1097/01.JU.0000556300.18991.8e
Walker, K., & Smith, J. (2019). Feasibility Study of Video Telehealth Clinic Visits in Urology. The Journal of Urology, 201(Supplement 4), e545-e545. https://www.auajournals.org/doi/10.1097/01.JU.0000556071.60611.37