HimsMental HealthPsychiatry

Feeling better
is possible.

Hims is here to help connect you with vetted professionals and, if prescribed, clinically proven medication.

How it works

Take an online mental health assessment
Get a prescription from a healthcare provider, if appropriate
Enjoy secure, ongoing support 100% online

Anxiety & depression medication

Medications psychiatrists trust. Try a consultation to see if it might be right for you.

Bupropion XL

Generic for Wellbutrin XL®

 

Important safety information

Buspirone HCI

Generic for Buspar®

 

Important safety information

Citalopram

Generic for Celexa®

 

Important safety information

Duloxetine

Generic for Cymbalta®

 

Important safety information

Escitalopram

Generic for Lexapro®

 

Important safety information

Fluoxetine

Generic for Prozac®

 

Important safety information

Sertraline

Generic for Zoloft®

 

Important safety information

Venlafaxine

Generic for Effexor®

 

Important safety information

What we treat

Let the pros make a plan. Whatever you’re going through, they tailor treatment to you.

Anxiety & depression

Not feeling like yourself? It could be anxiety or depression.

Sleep trouble

Your mental health affects more than you think.

Burnout & job stress

It’s been on the rise lately, and Hims can help.

Major life events

Whatever it is, you don’t have to go through it alone.

Featured reviews

Real results from guys like you

Kyle

“I truly felt like Hims took my symptoms and how I felt into careful consideration. Now, I know I can reach out to my practitioner at any time on my phone and can make adjustments as needed.”

 

Verified review

Sam

“I was able to secure an online appointment way faster than I had imagined and was back on my regular medication schedule within maybe a week or so of that consultation.”

 

Verified review

Nick

“I found support that I rarely experienced in a traditional clinical setting. They made me feel like there was no reason not to get help. No judgment. No unnecessary tests. Just support and solutions.”
 

Verified review

Jeff

“The process could not have been easier! I submitted a form and within the day I was chatting with a provider. I never felt judged.”
 

Verified review

Justin

“It has given me the treatment I needed without the hassle and perceived stigmas. I can’t thank Hims enough.”
 

Verified review

These customers’ results have not been independently verified. Individual results will vary. Customers were given free product.

Felt better

Over 75% of Hims customers who checked in with their provider reported improvements in their mental health symptoms.*

* Results vary. Data were self-reported between 11/26/2021 and 08/01/2022 by Hims customers who 1) signed up between 11/04/2021 and 05/04/2022; 2) were prescribed antidepressant medication by a provider after their first consultation on the Hims platform; and 3) had an active subscription for such antidepressant medication through the Hims platform within 90 days after signing up.

What you’ll get

Breaking down the cost of depression and anxiety treatment.
Medication - plans starting at just $49/mo, if prescribed
Provider evaluation - unlimited
Medication adjustments - unlimited
Ongoing follow-ups - unlimited

Subscription required. Actual price to customer will depend on product and subscription plan purchased. Prescription products require an online consultation with a…Read more

Judgment-free zone

Connect with vetted, licensed providers who are here to help.

  • Confidential online messaging
  • Simple medication management
  • Chat about what’s on your mind

    • Got questions?
    Get answers.

    You complete an intake form in the comfort of your own home and your answers are reviewed by a medical provider. Currently, our telepsychiatry services cover mental health issues related to depression and anxiety disorders. We do not currently provide access to treatment for other mental health conditions, such as post-traumatic stress disorder, eating disorders, ocd or obsessive-compulsive disorder, bipolar disorder, other mental illness, etc.
    In addition to psychiatry services and psychiatric medication, you can use our platform to connect with licensed therapists for online therapy (talk therapy).

    More for your mind

    First Psychiatry Session: What to Expect

    When To See a Psychiatrist


    We’ve got you

     

    Check-ins with licensed providers
     

    100% secure, online process
     

    No in-office visits required*

    * Asynchronous visits not available in all states.

    741-741

    If you're in emotional distress, text HOME to 741-741 to connect with a Crisis Text Line counselor immediately.

    911

    If you’re having a medical or mental health emergency, call 911 or go to your local ER.

    Important Safety Information

    The information below includes important safety information about bupropion ER XL, which is the generic version of the brand name drug Wellbutrin® XL. Read this information before you begin taking bupropion ER XL. You must notify your healthcare provider if you start or stop taking bupropion ER XL.
    Bupropion ER XL (bupropion hydrochloride) is a prescription medicine used to treat major depressive disorder (MDD), seasonal affective disorder (SAD), and to help people quit smoking (smoking cessation). Bupropion may also be helpful when prescribed “off-label” for bipolar disorder, attention deficit hyperactivity disorder (ADHD), and sexual dysfunction due to SSRI antidepressants.

    WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS
    Bupropion ER XL and other antidepressant medicines may increase suicidal thoughts or actions, in some people 24 years of age and younger within the first few months of treatment or when the dose is changed. Watch for these changes and inform your healthcare provider right away if you notice new or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe. Pay particular attention to such changes when bupropion ER XL is started or when the dose is changed.

    Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional. All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
    Do not take bupropion ER XL (bupropion hydrochloride) if you:
    • Are allergic to bupropion, as contained in bupropion hydrochloride, or any of the ingredients in bupropion
    • Take any medication for Parkinson’s Disease or depression called monoamine oxidase inhibitors (MAOI), or if you have stopped taking an MAOI in the last 14 days as they may cause a dangerous increase in blood pressure. MAOIs include, but are not limited to: isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine
    • Are already taking a medication containing bupropion
    • Are taking tamoxifen
    • Have a recent (within 5 years) history of a seizure disorder
    • Have a history of anorexia nervosa or bulimia nervosa
    • Drink large amounts of alcohol, use recreational drugs or abuse prescription medications - or suddenly stop substance abuse habits
    Inform your healthcare provider right away if you have any of the following symptoms, especially if they are new, worsening, or worry you:
    • Attempts to commit suicide
    • Acting aggressive or violent
    • New or worsening depression
    • Feeling agitated, restless, angry, or irritable
    • An increase in activity or talking more than what is normal for you
    • Acting on dangerous impulses
    • Thoughts about suicide or dying
    • New or worsening anxiety or panic attacks
    • Trouble sleeping
    • Other unusual changes in behavior or mood
    Bupropion ER XL may cause serious eye problems including a sudden decrease in vision with or without eye pain and redness, or a blockage of fluid in the eye causing increased pressure in the eye (secondary angle closure glaucoma). These eye problems are rare, but can lead to permanent loss of vision if not treated. You may want to undergo an eye examination to see if you are at risk and get preventative treatment if you are.
    Should you notice any new eye symptoms, including any new problems with your vision, immediately discontinue use of bupropion ER XL and seek urgent in-person evaluation. Please also message your provider team as soon as you are able.
    Before taking bupropion ER XL, inform your healthcare provider and pharmacist about all prescription and over-the-counter medications you are taking or plan to take, including supplements. This includes medications to treat migraines and psychiatric disorders (including other antidepressants or amphetamines). Reporting all medication and supplement use is necessary to avoid a potentially life-threatening condition called serotonin syndrome; report aspirin, other NSAID pain relievers, or other blood thinners because they may increase the risk of bleeding.
    Inform your healthcare provider immediately if you:
    • Become severely ill and have some or all of these symptoms: agitation, hallucinations, coma, or other changes in mental status; coordination problems or muscle twitching (overactive reflexes); fast, abnormal or racing heartbeat, high or low blood pressure; chest pain or pressure and shortness of breath; sweating or fever; nausea, vomiting, or diarrhea; muscle tightness, as these may be the symptoms of a life-threatening condition called serotonin syndrome
    • Have a rash, hives, swelling, or trouble breathing as these may be the symptoms of an allergic reaction
    • Have seizures or convulsions
    • Have any increased or unusual bruising or bleeding, especially if you take the blood thinner warfarin (Coumadin®, Jantoven®), a non-steroidal anti-inflammatory drug (NSAID), or aspirin
    • Have a headache; weakness or feeling unsteady; confusion, problems concentrating, thinking, or remembering, as these may be the symptoms of low salt (sodium) levels in the blood (hyponatremia). Elderly people may be at greater risk for this
    • Are pregnant, plan to become pregnant, or are breastfeeding
    Do not stop daily bupropion ER XL without first talking to your healthcare provider. Stopping bupropion ER XL abruptly may sometimes cause discontinuation symptoms, including anxiety, irritability, high or low mood, and feeling restless or sleepy. Discontinuation symptoms are less common with bupropion than with other antidepressants.
    Bupropion ER XL rarely causes sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You should not drive, operate heavy machinery, or do other dangerous activities until you know how bupropion ER XL affects you. Most people find it makes them more alert.
    Drinking alcohol on a regular basis while taking bupropion ER XL is not recommended. Occasional, moderate use appears to be safe.
    During treatment with this medication, common side effects of this medication may go away as your body adjusts to the medication. The most common side effects in adults treated with bupropion XL include:
    • Constipation
    • Mild diarrhea
    • Nausea and vomiting
    • Decrease in appetite
    • Dizziness
    • Increased sweating
    • Weight loss
    • Headache
    • Dry Mouth
    • Trouble sleeping
    • Sleepiness
    Swallow the tablet whole. Do not break, crush or chew it. For extended-release tablets, the tablet shell may be in your stool. This is normal and not cause for concern.
    If you miss a dose of this medicine, do not take an extra tablet to make up for the dose you forgot. Wait and take your next dose at your regular time the next day. Do not double dose.

    Important Safety Information

    The information below includes important safety information about buspirone, which is the generic version of the brand name drug BuSpar®. Buspirone is a prescription medication used for the treatment of generalized anxiety disorder (GAD) or the short-term relief of symptoms of anxiety and can be used off-label to augment treatment for unipolar depression. Read this information before you begin taking buspirone. You must notify your healthcare provider if you start or stop taking buspirone.

    Do not take buspirone if you:

    • Are allergic to buspirone, or any of the ingredients in buspirone
    • Have severe liver or kidney problems
    • Have benzodiazepine dependence
    • Take St John’s Wort or 5-Hydroxytryptophan (5-HTP)
    • Take any medicines for Parkinson’s Disease or depression called monoamine oxidase inhibitors (MAOI), or if you have stopped taking an MAOI in the last 14 days as they may cause a dangerous increase in blood pressure. MAOIs include, but are not limited to:
      • isocarboxazid
      • phenelzine
      • rasagiline
      • selegiline
      • tranylcypromine
    • Take other medication that may cause an increase in serotonin levels, such as
      • linezolid
      • methylene blue
      • tryptophan

    Before taking buspirone, inform your healthcare provider and pharmacist about all prescription medications you are taking or plan to take, including those to treat Parkinson’s Disease or psychiatric disorders (including antidepressants or amphetamines) to avoid a potentially life-threatening condition called Serotonin Syndrome or a dangerous increase in blood pressure. Inform your healthcare provider about any over-the-counter medications, vitamins, and natural supplements, such as St. John’s Wort, that you are taking or plan to take to help avoid potentially dangerous drug-drug interactions. Be sure to mention to your prescriber if you drink grapefruit juice or eat grapefruit regularly.

    Inform your healthcare provider immediately if you:

    • Become severely ill and have some or all of these symptoms: agitation, hallucinations, coma, or other changes in mental status; coordination problems or muscle twitching (overactive reflexes); racing heartbeat, high or low blood pressure; sweating or fever; nausea, vomiting, or diarrhea; muscle tightness, as these may be the symptoms of a life-threatening condition called Serotonin Syndrome
    • Develop restlessness or an inability to remain still, involuntary movements, hostility, or depression
    • Have a rash, hives, swelling, or trouble breathing as these may be the symptoms of an allergic reaction
    • Are pregnant, plan to become pregnant, or are breastfeeding

    Do not stop daily buspirone without first talking to your healthcare provider. Abruptly stopping can cause withdrawal symptoms including: vomiting, irritability, dizziness, headaches, sensation of tingling skin, or trouble sleeping.

    Until you experience how this medication affects you, do not drive a car, operate potentially dangerous machinery, or perform other dangerous activities.

    You should take buspirone consistently, either always with or always without food.

    During your treatment with buspirone, avoid drinking large amounts of grapefruit juice.

    Avoid drinking alcohol while taking buspirone.

    The most common side effects in adults treated with buspirone include:

    • Dizziness
    • Drowsiness
    • Diarrhea
    • Nausea
    • Headache
    • Insomnia
    • Mild congestion
    • A very rare but serious side effect that may occur with buspirone therapy is serotonin syndrome. The symptoms of serotonin syndrome include, but are not limited to, a change in mental status, trouble speaking or swallowing, excessive sweating, tremors, involuntary muscle contractions, and increased body temperature. Seek emergent medical care if you are experiencing any of these symptoms as they could be a sign of a life-threatening condition.

    If you miss a dose of buspirone, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and continue your regular dosing schedule. Do not double your next dose or take more than what is prescribed.

    Important Safety Information

    The information below includes important safety information about citalopram, which is the generic version of the brand name drug Celexa. Read this information before you begin taking citalopram. You must notify your healthcare provider if you start or stop taking citalopram.
    Citalopram is a prescription medicine used to treat depression. Citalopram can be used off-label to treat: obsessive-compulsive disorder, panic disorder (panic attacks), social phobia (also known as social anxiety disorder), posttraumatic stress disorder, eating disorders, premenstrual dysphoric disorder, and alcohol dependence.

    WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS
    Citalopram and other antidepressant medicines may increase suicidal thoughts or actions, especially in some people 24 years of age and younger within the first few months of treatment or when the dose is changed. If you are experiencing a mental health crisis, please call or text 988 to be connected with help, or go to your nearest hospital emergency department. Pay particular attention to such changes when citalopram is started or when the dose is changed.

    Do not take citalopram if you:
    • are allergic to citalopram, or any of the ingredients in Citalopram
    • Take any medication for Parkinson’s Disease or depression called monoamine oxidase inhibitors (MAOI), or if you have stopped taking an MAOI in the last 14 days as they may cause a dangerous increase in blood pressure. MAOIs include, but are not limited to: isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine
    • Take St John’s Wort or 5-Hydroxytryptophan (5-HTP)
    • are on methadone
    • are drinking large amounts of alcohol
    • are using or abusing recreation drugs or prescription medications
    Citalopram can cause serious side effects. Rarely reported side effects include:
    • increased bleeding (gums, unexplained bruising)
    • low sodium blood levels (symptoms may include headache, weakness and difficulty remembering or concentrating)
    • teeth grinding
    • seizure
    • angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye)
    • QT prolongation and ventricular arrhythmia including Torsades de Pointes (changes in the electrical activity of your heart; symptoms may include fast, slow or irregular heartbeat, shortness of breath, and dizziness or fainting)
    • serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death)
    Before you take citalopram, tell your healthcare provider if you: have thoughts of suicide or harming yourself have a history of psychiatric or medical problems, including bipolar disorder have taken any medication in the past for your condition, whether effective or not have suffered adverse or side effects from previous medication therapies drink alcohol or use/abuse recreational or prescription drugs are pregnant, plan to become pregnant, or are breastfeeding
    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and recreational drugs.
    Citalopram may affect the way other medicines work, and other medicines may affect the way citalopram works, causing side effects. Especially tell your healthcare provider if you take any of the following:
    • Aspirin or nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen, celecoxib, diclofenac)
    • Any other serotonergic medications including: trazodone, migraine medications (triptans), pain medications (tramadol), antibiotic linezolid, amphetamines
    • Warfarin or other anticoagulant therapy
    • certain antiarrhythmics: quinidine (Quinidex Extentabs®, Quinaglute®, Quinalan®), procainamide (Procanbid®, Pronestyl®, Pronestyl-SR®), amiodarone (Cordarone®, Pacerone®), sotalol (Betapace®, Sorine®)
    • certain antipsychotics: chlorpromazine (Thorazine®), thioridazine (Mellaril®)
    • certain antibiotics: gatifloxacin (Tequin®), moxifloxacin (Avelox®)
    • methadone
    During treatment with this medication, common side effects of this medication may go away as your body adjusts to the medication. The most common side effects of citalopram include: Mild diarrhea, constipation, nausea, vomiting, upset stomach, dry mouth, loss of appetite, weight loss, sweating, headache, dizziness, yawning, nervousness, tremor, weakness, pharyngitis, sexual side effects (such as erectile dysfunction, ejaculation disorder, or lowered interest in sex), unusual dreams, fatigue or feeling sleepy, and trouble sleeping.
    If you miss a dose of citalopram, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed.
    Do not abruptly stop taking citalopram even when you feel better. Abruptly stopping can cause withdrawal symptoms including: vomiting, irritability, dizziness, headaches, sensation of tingling skin, or nightmares.
    Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
    Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional. All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
    If you no longer need your medication, the best way to dispose of most types of old, unused, unwanted, or expired medicines (both prescription and over the counter) is to drop off the medicine at a drug take back site, location, or program immediately. You can use the DEA DIVERSION CONTROL DIVISION LOOKUP to find your nearest drug disposal site.
    If no drug take back sites, locations, or programs are available in your area, and there are no specific disposal instructions (such as flushing) in the medication guide or package insert, you can follow these simple steps to dispose of most medicines in your trash at home:
    • Mix medicines (liquid or pills; do not crush tablets or capsules) with an unappealing substance such as dirt, cat litter, or used coffee grounds;
    • Place the mixture in a container such as a sealed plastic bag;
    • Throw away the container in your trash at home; and
    • Delete all personal information on the prescription label of empty medicine bottles or medicine packaging, then trash or recycle the empty bottle or packaging.

    Important Safety Information

    The information below includes important safety information about duloxetine, which is the generic version of the brand name drug Cymbalta. Read this information before you begin taking duloxetine. You must notify your healthcare provider if you start or stop taking duloxetine.
    Duloxetine is a prescription medicine used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic peripheral neuropathic pain (DPNP), fibromyalgia, and chronic musculoskeletal pain.

    WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS
    Duloxetine and other antidepressant medicines may increase suicidal thoughts or actions, especially in some people 24 years of age and younger within the first few months of treatment or when the dose is changed. If you are experiencing a mental health crisis, please call or text 988 to be connected with help, or go to your nearest hospital emergency department. Pay particular attention to such changes when duloxetine is started or when the dose is changed.

    Do not take duloxetine if you:
    • are allergic to duloxetine, or any of the ingredients in duloxetine
    • Take any medication for Parkinson’s Disease or depression called monoamine oxidase inhibitors (MAOI), or if you have stopped taking an MAOI in the last 14 days as they may cause a dangerous increase in blood pressure. MAOIs include, but are not limited to: isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine
    • Take St John’s Wort or 5-Hydroxytryptophan (5-HTP)
    • have a medical history of a liver disease
    • are drinking large amounts of alcohol
    • are using or abusing recreation drugs or prescription medications
    Duloxetine can cause serious side effects. Rarely reported side effects include:
    • liver failure, sometimes fatal
    • orthostatic hypotension,a drop in blood pressure when standing or getting up from sleep
    • increased risk of bleeding
    • increased heart rate
    • irregular menstrual cycle
    • frequency of urination or difficulty urinating
    • angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye)
    • serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death)
    • hypertensive crisis
    • Stevens-Johnson Syndrome (rash)
    • pancreatitis
    Before you take duloxetine, tell your healthcare provider if you:
    • Have high blood pressure
    • have thoughts of suicide or harming yourself
    • have a history of psychiatric or medical problems, including bipolar disorder
    • have taken any medication in the past for your condition, whether effective or not
    • have suffered adverse or side effects from previous medication therapies
    • drink alcohol or use/abuse recreational or prescription drugs
    • are pregnant, plan to become pregnant, or are breastfeeding
    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and recreational drugs.
    Duloxetine may affect the way other medicines work, and other medicines may affect the way duloxetine works, causing side effects. Especially tell your healthcare provider if you take any of the following:
    • Aspirin or nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen, celecoxib, diclofenac)
    • Any other serotonergic medications including: trazodone, migraine medications (triptans), pain medications (tramadol), antibiotic linezolid, amphetamines
    • Warfarin or other anticoagulants
    • cimetidine (Tagamet®)
    • ciprofloxacin (Cipro®)
    During treatment with this medication, common side effects of this medication may go away as your body adjusts to the medication. The most common side effects of duloxetine: headache, dizziness, nausea, vomiting, upset stomach, diarrhea, dry mouth, constipation, loss of appetite, weight loss, increased sweating, feeling nervous, restless, fatigued, unusual dreams, sleepiness or trouble sleeping (insomnia). Sexual side effects (such as problems with orgasm or ejaculatory delay) or increased blood pressure may not improve over time.
    Swallow the capsule whole. Do not break, crush or chew it. If you miss a dose of duloxetine take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed.
    Do not abruptly stop taking duloxetine even when you feel better. Abruptly stopping can cause withdrawal symptoms including: vomiting, irritability, dizziness, headaches, sensation of tingling skin, or nightmares.
    Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
    Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional. All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
    If you no longer need your medication, the best way to dispose of most types of old, unused, unwanted, or expired medicines (both prescription and over the counter) is to drop off the medicine at a drug take back site, location, or program immediately. You can use the DEA DIVERSION CONTROL DIVISION LOOKUP to find your nearest drug disposal site.
    If no drug take back sites, locations, or programs are available in your area, and there are no specific disposal instructions (such as flushing) in the medication guide or package insert, you can follow these simple steps to dispose of most medicines in your trash at home:
    • Mix medicines (liquid or pills; do not crush tablets or capsules) with an unappealing substance such as dirt, cat litter, or used coffee grounds;
    • Place the mixture in a container such as a sealed plastic bag;
    • Throw away the container in your trash at home; and
    • Delete all personal information on the prescription label of empty medicine bottles or medicine packaging, then trash or recycle the empty bottle or packaging.

    Important Safety Information

    The information below includes important safety information about escitalopram, which is the generic version of the brand name drug Lexapro. Read this information before you begin taking escitalopram. You must notify your healthcare provider if you start or stop taking escitalopram.
    Escitalopram is a prescription medicine used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram may also be helpful when prescribed “off-label” for obsessive compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder.

    WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS
    Escitalopram and other antidepressant medicines may increase suicidal thoughts or actions, especially in some people 24 years of age and younger within the first few months of treatment or when the dose is changed. If you are experiencing a mental health crisis, please call or text 988 to be connected with help, or go to your nearest hospital emergency department. Pay particular attention to such changes when escitalopram is started or when the dose is changed.

    Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional. All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
    Do not take Escitalopram if you:
    • are allergic to escitalopram, or any of the ingredients in escitalopram
    • Take any medication for Parkinson’s Disease or depression called monoamine oxidase inhibitors (MAOI), or if you have stopped taking an MAOI in the last 14 days as they may cause a dangerous increase in blood pressure. MAOIs include, but are not limited to: isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine
    • Take St John’s Wort or 5-Hydroxytryptophan (5-HTP)
    • also take pimozide (Orap) or citalopram (Celexa)
    • are drinking large amounts of alcohol
    • are using or abusing recreation drugs or prescription medications
    Escitalopram can cause serious side effects. Rarely reported side effects include:
    • increased bleeding (gums)
    • low sodium blood levels (symptoms may include headache, weakness and difficulty remembering or concentrating)
    • teeth grinding
    • seizure
    • angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye)
    • QT prolongation and ventricular arrhythmia including Torsades de Pointes (changes in the electrical activity of your heart; symptoms may include fast, slow or irregular heartbeat, shortness of breath, and dizziness or fainting)
    • serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death)
    Before you take escitalopram, tell your healthcare provider if you:
    • have thoughts of suicide or harming yourself
    • have a history of psychiatric or medical problems, including bipolar disorder
    • have taken any medication in the past for your condition, whether effective or not
    • have suffered adverse or side effects from previous medication therapies
    • drink alcohol or use/abuse recreational or prescription drugs
    • are pregnant, plan to become pregnant, or are breastfeeding
    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and recreational drugs.
    Escitalopram may affect the way other medicines work, and other medicines may affect the way escitalopram works, causing side effects. Especially tell your healthcare provider if you take any of the following:
    • Aspirin or nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen, celecoxib, diclofenac)
    • Warfarin or other anticoagulants
    • Any other serotonergic medications including: trazodone, migraine medications (triptans), pain medications (tramadol), antibiotic linezolid, amphetamines
    During treatment with this medication, common side effects of this medication may go away as your body adjusts to the medication. The most common side effects of escitalopram include: headache, dizziness, nausea, vomiting, diarrhea, constipation, upset stomach, nose or throat irritation, dry mouth, loss of appetite, weight loss, increased sweating, yawning, feeling nervous, restless, fatigued, tremor, unusual dreams, sleepiness or having trouble sleeping (insomnia). Sexual side effects, such as problems with orgasm or ejaculatory delay, often do not diminish over time.
    If you miss a dose of escitalopram, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed.
    Do not abruptly stop taking escitalopram even when you feel better. Abruptly stopping can cause withdrawal symptoms including: vomiting, irritability, dizziness, headaches, sensation of tingling skin, or nightmares.
    Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
    If you no longer need your medication, the best way to dispose of most types of old, unused, unwanted, or expired medicines (both prescription and over the counter) is to drop off the medicine at a drug take back site, location, or program immediately. You can use the DEA DIVERSION CONTROL DIVISION LOOKUP to find your nearest drug disposal site.
    If no drug take back sites, locations, or programs are available in your area, and there are no specific disposal instructions (such as flushing) in the medication guide or package insert, you can follow these simple steps to dispose of most medicines in your trash at home:
    • Mix medicines (liquid or pills; do not crush tablets or capsules) with an unappealing substance such as dirt, cat litter, or used coffee grounds;
    • Place the mixture in a container such as a sealed plastic bag;
    • Throw away the container in your trash at home; and
    • Delete all personal information on the prescription label of empty medicine bottles or medicine packaging, then trash or recycle the empty bottle or packaging.

    Important Safety Information

    The information below includes important safety information about fluoxetine, which is the generic version of the brand name drug Prozac. Read this information before you begin taking fluoxetine. You must notify your healthcare provider if you start or stop taking fluoxetine.
    Fluoxetine is a prescription medicine used to treat major depressive disorder (MDD), obsessive compulsive disorder (OCD), panic disorder, bulimia nervosa, and premenstrual dysphoric disorder (PMDD). Fluoxetine may also be helpful when prescribed “off-label” for body dysmorphic disorder, dysthymia, or posttraumatic stress disorder (PTSD).

    WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS
    Fluoxetine and other antidepressant medicines may increase suicidal thoughts or actions, especially in some people 24 years of age and younger within the first few months of treatment or when the dose is changed. If you are experiencing a mental health crisis, please call or text 988 to be connected with help, or go to your nearest hospital emergency department. Pay particular attention to such changes when fluoxetine is started or when the dose is changed.

    Do not take Fluoxetine if you:
    • are allergic to fluoxetine, or any of the ingredients in fluoxetine
    • Take any medication for Parkinson’s Disease or depression called monoamine oxidase inhibitors (MAOI), or if you have stopped taking an MAOI in the last 14 days as they may cause a dangerous increase in blood pressure. MAOIs include, but are not limited to: isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine
    • Take St John’s Wort or 5-Hydroxytryptophan (5-HTP)
    • taking tamoxifen
    • are drinking large amounts of alcohol
    • are using or abusing recreation drugs or prescription medications
    Fluoxetine can cause serious side effects. Rarely reported side effects include:
    • low sodium blood levels (symptoms may include headache, weakness, difficulty remembering or concentrating, feeling confused, seizures, change in balance, a significant weight gain or loss)
    • angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye)
    • serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death)
    • increased bleeding (gums)
    • Seizures
    • Dizziness
    • Slow heartbeat
    • Menstrual changes
    • Passing urine more often
    • Trouble controlling body movements
    • Erection that lasts more than 4 hours
    • teeth grinding
    • QT prolongation and ventricular arrhythmia including Torsades de Pointes (changes in the electrical activity of your heart; symptoms may include fast, slow or irregular heartbeat, shortness of breath, and dizziness or fainting)
    • increased risk of bleeding events when combined with use of aspirin, nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen), warfarin, and other anticoagulants
    Before you take fluoxetine, tell your healthcare provider if you:
    • have thoughts of suicide or harming yourself
    • have a history of psychiatric or medical problems, including bipolar disorder
    • have taken any medication in the past for your condition, whether effective or not
    • have suffered adverse or side effects from previous medication therapies
    • drink alcohol or use/abuse recreational or prescription drugs
    • are pregnant, plan to become pregnant, or are breastfeeding
    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and recreational drugs.
    Fluoxetine may affect the way other medicines work, and other medicines may affect the way fluoxetine works, causing side effects. Especially tell your healthcare provider if you take any of the following:
    • Aspirin or nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen, celecoxib, diclofenac)
    • Warfarin or other anticoagulants
    • Any other serotonergic medications including: trazodone, migraine medications (triptans), pain medications (tramadol), antibiotic linezolid, amphetamines
    • anticonvulsants (phenytoin, carbamazepine)
    • antipsychotics (haloperidol, aripiprazole)
    • atomoxetine
    • tricyclic antidepressants (imipramine, desipramine)
    • beta blockers (metoprolol, propranolol)
    • tamoxifen
    During treatment with this medication, the side effects of this medication may go away as your body adjusts to the medication. The most common side effects of fluoxetine include: headache, nausea, vomiting, diarrhea, constipation, upset stomach, decreased appetite, flu-like symptoms, dry mouth, nose or throat irritation, increased sweating, feeling nervous, restlessness, shakiness, fatigue, yawning, hot flashes, unusual dreams, sleepiness or having trouble sleeping (insomnia). Sexual side effects, such as problems with orgasm or ejaculatory delay often do not diminish over time.
    The delayed release form should be swallowed whole. Do not break, crush or chew it.
    If you miss a dose of fluoxetine that you take daily, take it as soon as you remember, unless it is closer to the time of your next dose. If you take fluoxetine once weekly, take it as soon as possible, then go back to your regular schedule the next week. Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed.
    Do not stop taking fluoxetine, even when you feel better. Abruptly stopping can cause withdrawal symptoms including: vomiting, irritability, dizziness, headaches, sensation of tingling skin, or nightmares.
    Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
    Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional. All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
    If you no longer need your medication, the best way to dispose of most types of old, unused, unwanted, or expired medicines (both prescription and over the counter) is to drop off the medicine at a drug take back site, location, or program immediately. You can use the DEA DIVERSION CONTROL DIVISION LOOKUP to find your nearest drug disposal site.
    If no drug take back sites, locations, or programs are available in your area, and there are no specific disposal instructions (such as flushing) in the medication guide or package insert, you can follow these simple steps to dispose of most medicines in your trash at home:
    • Mix medicines (liquid or pills; do not crush tablets or capsules) with an unappealing substance such as dirt, cat litter, or used coffee grounds;
    • Place the mixture in a container such as a sealed plastic bag;
    • Throw away the container in your trash at home; and
    • Delete all personal information on the prescription label of empty medicine bottles or medicine packaging, then trash or recycle the empty bottle or packaging

    Important Safety Information

    Do not take Paroxetine if you:
    • are allergic to Paroxetine, or any of the ingredients in Fluoxetine
    • take any medicines called monoamine oxidase inhibitor (MAOI), or if you have stopped taking an MAOI within the last 14 days
    • taking thioridazine
    • taking tamoxifen
    • taking pimozide
    • are drinking alcohol
    • are using or abusing recreation drugs or prescription medications
    Paroxetine can cause serious side effects. Rarely reported side effects include:
    • low sodium blood levels (symptoms may include headache, weakness and difficulty remembering or concentrating)
    • teeth grinding
    • angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye)
    • serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death)
    • seizure
    • increased risk of bleeding events when combined with use of aspirin, nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen), warfarin, and other anticoagulants
    Before you take Paroxetine, tell your healthcare provider if you:
    • have thoughts of suicide or harming yourself
    • have a history of psychiatric or medical problems, including bipolar disorder
    • have taken any medication in the past for your condition, whether effective or not
    • have suffered adverse or side effects from previous medication therapies
    • are receiving any non-medication treatment, such as talk therapy
    • drink alcohol or use/abuse recreational or prescription drugs
    • are pregnant, plan to become pregnant, or are breastfeeding
    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and recreational drugs.
    Paroxetine may affect the way other medicines work, and other medicines may affect the way Paroxetine works, causing side effects. Especially tell your healthcare provider if you take any of the following:
    • any other serotonergic medications, migraine medications (triptans), pain medications, antibiotic linezolid, amphetamines
    • atomoxetine
    • antipsychotics (aripiprazole, risperidone)
    • warfarin
    • cardiac medications (propafenone, metoprolol, propranolol)
    • tricyclic antidepressants (desipramine, imipramine)
    During treatment with this medication, the side effects of this medication may go away as your body adjusts to the medication. The most common side effects of Paroxetine: Headache, nausea, constipation, diarrhea, dry mouth, increased sweating, and dizziness, feeling nervous, restless, fatigued, sleepy, or having trouble sleeping (insomnia). Sexual side effects, such as problems with orgasm or ejaculatory delay often do not diminish over time.
    Paroxetine is a prescription medicine used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (social phobia), panic disorder, obsessive compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD).
    The controlled release form should be swallowed whole. Do not break, crush or chew it.
    If you miss a dose of paroxetine, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed.
    Do not stop taking paroxetine, even when you feel better. Abruptly stopping can cause withdrawal symptoms including: nausea, sweating, dysphoric mood, irritability, agitation, dizziness, sensory disturbances as electric shock sensations, tremor, anxiety, confusion, headache, lethargy, emotional lability, insomnia, hypomania, ringing in the ears, and seizures.
    Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
    Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional. All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
    If you no longer need your medication, the best way to dispose of most types of old, unused, unwanted, or expired medicines (both prescription and over the counter) is to drop off the medicine at a drug take back site, location, or program immediately. You can use the DEA DIVERSION CONTROL DIVISION LOOKUP to find your nearest drug disposal site.
    If no drug take back sites, locations, or programs are available in your area, and there are no specific disposal instructions (such as flushing) in the medication guide or package insert, you can follow these simple steps to dispose of most medicines in your trash at home:
    • Mix medicines (liquid or pills; do not crush tablets or capsules) with an unappealing substance such as dirt, cat litter, or used coffee grounds;
    • Place the mixture in a container such as a sealed plastic bag;
    • Throw away the container in your trash at home; and
    • Delete all personal information on the prescription label of empty medicine bottles or medicine packaging, then trash or recycle the empty bottle or packaging.

    Important Safety Information

    The information below includes important safety information about sertraline, which is the generic version of the brand name drug Zoloft. Read this information before you begin taking sertraline. You must notify your healthcare provider if you start or stop taking sertraline.
    Sertraline is a prescription medicine used to treat major depressive disorder (MDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder, and social anxiety disorder. Sertraline may also be helpful when prescribed “off-label” for binge-eating disorder, bulimia nervosa, and generalized anxiety disorder (GAD).

    WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS
    Sertraline and other antidepressant medicines may increase suicidal thoughts or actions, especially in some people 24 years of age and younger within the first few months of treatment or when the dose is changed. If you are experiencing a mental health crisis, please call or text 988 to be connected with help, or go to your nearest hospital emergency department. Pay particular attention to such changes when sertraline is started or when the dose is changed.

    Do not take sertraline if you:
    • are allergic to sertraline, or any of the ingredients in sertraline
    • Take any medication for Parkinson’s Disease or depression called monoamine oxidase inhibitors (MAOI), or if you have stopped taking an MAOI in the last 14 days as they may cause a dangerous increase in blood pressure. MAOIs include, but are not limited to: isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine
    • Take St John’s Wort or 5-Hydroxytryptophan (5-HTP)
    • are taking pimozide
    • are drinking large amounts of alcohol
    • are abusing recreation drugs or prescription medications
    Sertraline can cause serious side effects. Rarely reported side effects include:
    • low sodium blood levels (symptoms may include headache, weakness and difficulty remembering or concentrating)
    • teeth grinding
    • angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye)
    • serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death)
    • seizure
    • increased risk of bleeding events when combined with use of aspirin, nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen), warfarin, and other anticoagulants
    Before you take sertraline, tell your healthcare provider if you:
    • have thoughts of suicide or harming yourself
    • have a history of psychiatric or medical problems, including bipolar disorder
    • have taken any medication in the past for your condition, whether effective or not
    • have suffered adverse or side effects from previous medication therapies
    • drink alcohol or use/abuse recreational or prescription drugs
    • are pregnant, plan to become pregnant, or are breastfeeding
    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and recreational drugs.
    Sertraline may affect the way other medicines work, and other medicines may affect the way sertraline works, causing side effects. Especially tell your healthcare provider if you take any of the following:
    • Any other serotonergic medications including: trazodone, migraine medications (triptans), pain medications (tramadol), antibiotic linezolid, amphetamines
    • Aspirin or nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen, celecoxib, diclofenac)
    • Warfarin or other anticoagulants
    During treatment with this medication, the side effects of this medication may go away over the first week or two as your body adjusts to the medication. The most common side effects of sertraline: Headache, dizziness, loss of appetite, weight loss, nausea, vomiting, diarrhea, dry mouth, increased sweating, yawning, tremor, feeling nervous, restless, fatigue, unusual dreams, sleepiness or having trouble sleeping (insomnia). Sexual side effects, such as problems with orgasm or ejaculatory delay often do not diminish over time.
    If you miss a dose of sertraline abruptly, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed.
    Do not stop taking sertraline, even when you feel better. Abruptly stopping can cause withdrawal symptoms including: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).
    Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
    Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional. All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
    If needed, the best way to dispose of most types of old, unused, unwanted, or expired medicines (both prescription and over the counter) is to drop off the medicine at a drug take back site, location, or program immediately. You can use the DEA DIVERSION CONTROL DIVISION LOOKUP to find your nearest drug disposal site.
    If you no longer need your medication, locations, or programs are available in your area, and there are no specific disposal instructions (such as flushing) in the medication guide or package insert, you can follow these simple steps to dispose of most medicines in your trash at home:
    • Mix medicines (liquid or pills; do not crush tablets or capsules) with an unappealing substance such as dirt, cat litter, or used coffee grounds;
    • Place the mixture in a container such as a sealed plastic bag;
    • Throw away the container in your trash at home; and
    • Delete all personal information on the prescription label of empty medicine bottles or medicine packaging, then trash or recycle the empty bottle or packaging.

    Important Safety Information

    The information below includes important safety information about venlafaxine ER, which is the generic version of the brand name drug Effexor XL. Read this information before you begin taking venlafaxine ER. You must notify your healthcare provider if you start or stop taking venlafaxine ER.
    Venlafaxine ER is a prescription medicine used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder, and social anxiety disorder (social phobia. Extended release tablets should be swallowed whole. Do not break, crush or chew it. Extended release capsules: swallow whole or sprinkle onto food, such as applesauce or pudding and eat immediately.

    WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS
    Venlafaxine ER and other antidepressant medicines may increase suicidal thoughts or actions, especially in some people 24 years of age and younger within the first few months of treatment or when the dose is changed. If you are experiencing a mental health crisis, please call or text 988 to be connected with help, or go to your nearest hospital emergency department. Pay particular attention to such changes when venlafaxine ER is started or when the dose is changed.

    Do not take venlafaxine if you:
    • are allergic to venlafaxine, or any of the ingredients in venlafaxine ER
    • Take any medication for Parkinson’s Disease or depression called monoamine oxidase inhibitors (MAOI), or if you have stopped taking an MAOI in the last 14 days as they may cause a dangerous increase in blood pressure. MAOIs include, but are not limited to: isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine
    • Take St John’s Wort or 5-Hydroxytryptophan (5-HTP)
    • are drinking large amounts of alcohol
    • are using or abusing recreation drugs or prescription medications
    Venlafaxine ER can cause serious side effects. Rarely reported side effects include:
    • increased heart rate, low blood pressure
    • increased salivation
    • irregular menstrual cycle
    • increased frequency of urination, difficulty urinating
    • changes in taste
    • low sodium (symptoms of low sodium levels may include headache, weakness, difficulty concentrating and remembering)
    • teeth grinding
    • angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye)
    • serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death)
    • increased risk of bleeding events when combined with use of aspirin, nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen), warfarin, and other anticoagulants
    Before you take venlafaxine ER, tell your healthcare provider if you:
    • have thoughts of suicide or harming yourself
    • have a history of psychiatric or medical problems, including bipolar disorder
    • have taken any medication in the past for your condition, whether effective or not
    • have suffered adverse or side effects from previous medication therapies
    • drink alcohol or use/abuse recreational or prescription drugs
    • are pregnant, plan to become pregnant, or are breastfeeding
    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and recreational drugs.
    Venlafaxine ER may affect the way other medicines work, and other medicines may affect the way venlafaxine ER works, causing side effects. Especially tell your healthcare provider if you take any of the following:
    • Any other serotonergic medications including: trazodone, migraine medications (triptans), pain medications (tramadol), antibiotic linezolid, amphetamines
    • Aspirin or nonsteroidal anti-inflammatory drugs (e.g. ibuprofen, naproxen, celecoxib, diclofenac)
    • Warfarin or other anticoagulants
    During treatment with this medication, the side effects of this medication may go away over the first one to two weeks your body adjusts to the medication. The most common side effects of venlafaxine include: headache, dizziness, shakiness, nausea, diarrhea, constipation, gas, upset stomach, dry mouth, weight loss, loss of appetite, increased sweating, feeling nervous, anxiety, restlessness, fatigue, yawning, unusual dreams, sleepiness or having trouble sleeping (insomnia). Sexual side effects, such as problems with orgasm or ejaculatory delay, or increased blood pressure often do not improve over time.
    If you miss a dose of venlafaxine ER, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed.
    Do not stop taking venlafaxine ER abruptly, even when you feel better. Abruptly stopping can cause withdrawal symptoms including: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).
    Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
    Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional. All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
    If you no longer need your medication, the best way to dispose of most types of old, unused, unwanted, or expired medicines (both prescription and over the counter) is to drop off the medicine at a drug take back site, location, or program immediately. You can use the DEA DIVERSION CONTROL DIVISION LOOKUP to find your nearest drug disposal site.
    If no drug take back sites, locations, or programs are available in your area, and there are no specific disposal instructions (such as flushing) in the medication guide or package insert, you can follow these simple steps to dispose of most medicines in your trash at home:
    • Mix medicines (liquid or pills; do not crush tablets or capsules) with an unappealing substance such as dirt, cat litter, or used coffee grounds;
    • Place the mixture in a container such as a sealed plastic bag;
    • Throw away the container in your trash at home; and
    • Delete all personal information on the prescription label of empty medicine bottles or medicine packaging, then trash or recycle the empty bottle or packaging.

    * Controlled substances, including amphetamines (such as Adderall) or benzodiazepines (such as Xanax and Valium) are not available through our platform.

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