FDA approved

Generic for Effexor®Venlafaxine

Starting at $49/mo

Getting psychiatric care for anxiety and depression has never been simpler. Consult with a licensed healthcare provider to determine whether a medication like venlafaxine could be right for you.

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Prescribed by a healthcare provider experienced in treating anxiety & depression, if appropriate

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Unlimited provider messaging

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Unlimited dosage adjustments

What is venlafaxine?

Venlafaxine is a prescription drug, notably the first of a newer type called SNRIs (serotonin-norepinephrine reuptake inhibitors) that offer an alternative to SSRIs (selective serotonin reuptake inhibitors). The Food and Drug Administration first approved the drug in 1993 to treat depression in adults and later in 1997 as an extended release (XR) version. It is marketed under the brand name Effexor®.

Venlafaxine uses

Venlafaxine (generic for Effexor XR®) is approved by the FDA to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety order (SAD), and panic disorder (PD). Not all mental health conditions can be treated by a provider through our platform. Those who are not candidates for treatment through our platform should consider seeking care from a medical provider in person to evaluate potential options for treatment.

How venlafaxine works

Venlafaxine affects the balance of two chemicals within the brain. Like other SNRIs, venlafaxine specifically inhibits the nervous system from reabsorbing both serotonin and norepinephrine. Relative to other SNRIs, venlafaxine targets serotonin more than norepinephrine.

Venlafaxine drug interactions

Monoamine oxidase inhibitors (MAOIs, such as linezolid, methylene blue, etc), increase the risk of serotonin syndrome, a mild to life-threatening build up of serotonin in the system. Similarly, venlafaxine can interact with other agents that affect serotonin in the brain, such as tricyclic antidepressants, certain pain medications, supplements that contain St. John's Wort or tryptophan. Be prepared to share all prescription and over the counter medications, as well as any other products you take, with your provider.

* Only available if prescribed after an online consultation with a healthcare provider.

* Controlled substances such as Xanax and Adderall are not available through our platform.

* This page has been medically reviewed by Sylvia Valadez, MSN, APRN, FNP-BC.

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Generic for Effexor®

How to get venlafaxine online with Hims

1. Simple consultation

Complete an online mental health assessment and intake form, then connect with a healthcare provider through our platform.

2. Free delivery

Get venlafaxine shipped to you for free, if prescribed.

3. Ongoing support

Enjoy secure, ongoing support 100% online—including refills and unlimited dosage adjustments.

Venlafaxine 101

What’s an SNRI?

Serotonin-norepinephrine reuptake inhibitors (SNRIs) zero in on mood-affecting chemicals in the brain and help to regulate their levels to improve your symptoms. Nice, right?

The science of venlafaxine

Your brain naturally makes chemicals that make you feel good, like serotonin and norepinephrine. Venlafaxine keeps neurons from reabsorbing these chemicals so that you have more of them available in your brain, and focuses more on serotonin than other SNRIs. Long story short? This can help relieve symptoms of anxiety and depression.

Felt better

Over 75% of Hims customers who checked in with their provider reported improvements in their mental health symptoms.*

* Results vary. Data were self-reported between 11/26/2021 and 08/01/2022 by Hims customers who 1) signed up between 11/04/2021 and 05/04/2022; 2) were prescribed antidepressant medication by a provider after their first consultation on the Hims platform; and 3) had an active subscription for such antidepressant medication through the Hims platform within 90 days after signing up.


You’re in good hands

Before they're accepted to the pool of professionals we work with, all healthcare providers undergo a rigorous vetting process. They have years of experience and they’re ready to help with whatever you’re going through.

Frequently asked questions about venlafaxine

How long does it take for venlafaxine (generic for Effexor) to work?

Venlafaxine was shown to be effective as a treatment for major depressive disorder in clinical trials lasting 8-12 weeks and as a treatment for generalized anxiety disorder in clinical trials lasting 8 weeks to 6 months. If you start taking venlafaxine and do not feel any improvement in your condition, talk to your healthcare provider. Do not stop taking venlafaxine without consulting your doctor.

Does venlafaxine cause hair loss?

Hair loss is not a generally recognized side effect of venlafaxine. However, all medications carry a risk of new or unusual side effects. If you start taking venlafaxine and notice a significant increase in hair loss, talk to your healthcare provider.

Can you get venlafaxine online?

Consult with a psychiatrist or other qualified psychiatry provider online through our platform. If prescribed venlafaxine, genuine venlafaxine XR will be shipped to you discreetly. You’ll have ongoing check-ins with a healthcare provider to evaluate whether your treatment plan is working.

Does venlafaxine interact with other drugs?

Monoamine oxidase inhibitors (MAOIs, such as linezolid, methylene blue, etc), increase the risk of serotonin syndrome, a mild to life-threatening build up of serotonin in the system. Similarly, venlafaxine can interact with other agents that affect serotonin in the brain, such as tricyclic antidepressants, certain pain medications, supplements that contain St. John's Wort or tryptophan. Be prepared to share all prescription and over the counter medications, as well as any other products you take, with your provider to avoid any adverse effects.

Who should not take venlafaxine?

You should seek medical advice from a healthcare professional before taking venlafaxine if you have any of the following medical conditions: seizures, high blood pressure, high cholesterol, glaucoma, kidney disease, or liver disease. You should also talk to your doctor before taking venlafaxine if you are breastfeeding. Talk to a health care professional about drug information, common or more serious side effects, and potential withdrawal symptoms.

Does venlafaxine make you gain weight?

One possible side effect of venlafaxine is weight changes, such as weight loss or weight gain. Some patients experience a sudden drop in appetite, which can cause rapid or unhealthy weight loss.

Is venlafaxine a controlled substance?

No, venlafaxine is not considered a controlled substance according to the Controlled Substances Act. It is a serotonin-norepinephrine reuptake inhibitor. Because SNRIs are generally considered non-addictive, they do not fall under the controlled substance category.

Learn more about venlafaxine

Important safety information

Learn more about venlafaxine

Important safety information

741-741

If you're in emotional distress, text HOME to 741-741 to connect with a Crisis Text Line counselor immediately.

911

If you’re having a medical or mental health emergency, call 911 or go to your local ER.

More for your mind

Venlafaxine Dosage Guide

How Long Does It Take For Effexor To Work

* Controlled substances, including amphetamines (such as Adderall) or benzodiazepines (such as Xanax and Valium) are not available through our platform.