FDA approved

Generic for Prozac®Fluoxetine

Starting at $49/mo

Getting psychiatric care for anxiety and depression has never been simpler. Consult with a licensed healthcare provider to determine whether a medication like fluoxetine could be right for you.



Prescribed by a healthcare provider experienced in treating anxiety & depression, if appropriate


Unlimited provider messaging


Unlimited dosage adjustments

What is fluoxetine?

Fluoxetine is an antidepressant, notably the first SSRI (selective serotonin reuptake inhibitor) approved for use in the United States. It has been approved by the FDA and marketed under the brand name Prozac® for over three decades.

Fluoxetine uses

  • Currently, fluoxetine is FDA-approved for acute and maintenance treatment of major depressive disorder (MDD), as well as obsessive-compulsive disorder (OCD), bulimia nervosa, and panic disorder. Not all mental health conditions can be treated by a provider through our platform.
  • Fluoxetine should be taken exactly as directed by your healthcare provider. Generally, it is taken once a day at the same time, earlier in the day if trouble sleeping is a concern. Abruptly stopping fluoxetine is generally not recommended, even if you feel better, because serious withdrawal symptoms can occur.

How fluoxetine works

Fluoxetine works to increase the amount of serotonin in the brain by limiting how much serotonin is reabsorbed by nerve cells. For people with depression and anxiety, this can help manage symptoms such as low interest in activities or panic attacks.

* Only available if prescribed after an online consultation with a healthcare provider.

* Controlled substances such as Xanax and Adderall are not available through our platform.

* This page has been medically reviewed by Sylvia Valadez, MSN, APRN, FNP-BC.

Select your plan

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Generic for Prozac®

How to get fluoxetine online with Hims

1. Simple consultation

Complete an online mental health assessment and intake form, then connect with a healthcare provider through our platform.

2. Free delivery

Get fluoxetine shipped to you for free, if prescribed.

3. Ongoing support

Enjoy secure, ongoing support 100% online—including refills and unlimited dosage adjustments.

Fluoxetine 101

What’s an SSRI?

Selective serotonin reuptake inhibitors (SSRIs) are a type of antidepressant that work by increasing levels of a mood-affecting chemical called serotonin in the brain which helps to improve your symptoms. Nice, right?

The science of fluoxetine

Your brain naturally produces chemicals that make you feel good, like serotonin. Fluoxetine keeps neurons from reabsorbing this chemical so that you have more of it available in your brain. Long story short? For people with depression and anxiety disorders, this can help to improve interest in activities or reduce the number of panic attacks.

Felt better

Over 75% of Hims customers who checked in with their provider reported improvements in their mental health symptoms.*

* Results vary. Data were self-reported between 11/26/2021 and 08/01/2022 by Hims customers who 1) signed up between 11/04/2021 and 05/04/2022; 2) were prescribed antidepressant medication by a provider after their first consultation on the Hims platform; and 3) had an active subscription for such antidepressant medication through the Hims platform within 90 days after signing up.

You’re in good hands

Before they're accepted to the pool of professionals we work with, all healthcare providers undergo a rigorous vetting process. They have years of experience and they’re ready to help with whatever you’re going through.

Frequently asked questions about fluoxetine

How does fluoxetine (generic for Prozac) make you feel?

Fluoxetine has been shown to be effective in treating depression and certain types of anxiety in clinical trials.

How do you use fluoxetine (generic for Prozac)?

Always take fluoxetine exactly as directed by your healthcare provider. Dosing instructions may differ for you. Abruptly stopping fluoxetine is generally not recommended, even if you feel better, because serious withdrawal symptoms can occur. As such, providers often recommend patients take a missed dose of fluoxetine as soon as possible unless the next scheduled dosing time is near.

Is fluoxetine (generic for Prozac) addictive?

Fluoxetine has not been systematically studied for its potential for abuse, tolerance, or physical dependence and is not known to have addictive properties. Quitting fluoxetine without talking to a healthcare provider is not recommended, as discontinuing fluoxetine could cause serious discontinuation symptoms. You should always consult a healthcare provider before stopping fluoxetine.

Does fluoxetine (generic for Prozac) cause weight gain?

While antidepressants are sometimes associated with minor weight gain, in clinical studies of fluoxetine, a small number of patients reported decreased appetite and/or weight loss, which may be more significant in underweight depressed or bulimic patients. Consult your healthcare provider with any questions about the potential for weight gain while taking fluoxetine.

Where can I buy fluoxetine online?

Consult with a psychiatrist or other qualified psychiatry provider online through our platform. If prescribed fluoxetine, genuine fluoxetine hydrochloride (HCl) will be shipped to you discreetly. You’ll have ongoing check-ins with a health care provider to evaluate how your treatment plan is working and adjust dosing as needed.

Who should not consider fluoxetine?

Fluoxetine is not appropriate for everyone or all conditions. You should seek medical advice from another healthcare provider if you have any of the following mental health conditions:
  • ADHD
  • schizophrenia
  • bipolar disorder

What drugs interact with fluoxetine?

Interactions between fluoxetine and other substances can occur. Interaction risks include but are not limited to:
  • monoamine oxidase inhibitors (MAOI) drugs (eg, selegiline, tranylcypromine, phenelzine, isocarboxazid, linezolid)
  • other antidepressants (such as alprazolam or diazepam, which can cause a rare but serious condition known as serotonin syndrome),
  • NSAIDs (eg, naproxen, ibuprofen)
  • blood thinners such as warfarin
  • certain recreational drugs including alcohol or MDMA ("ecstasy"), and the herbal supplement St. John's Wort
  • Drugs that slow down Prozac effectiveness, such as pimozide, thioridazine, vinblastine or tricyclic antidepressants (eg, desipramine, imipramine), among others.
Be prepared to share all prescription and over the counter medications, as well as any other products you take, with your healthcare provider. Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.

Learn more about fluoxetine

Important safety information

Learn more about fluoxetine

Important safety information


If you're in emotional distress, text HOME to 741-741 to connect with a Crisis Text Line counselor immediately.


If you’re having a medical or mental health emergency, call 911 or go to your local ER.

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* Controlled substances, including amphetamines (such as Adderall) or benzodiazepines (such as Xanax and Valium) are not available through our platform.