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Enjoy sex like you used to
Stree Overlord Strong tablets are male-enhancement pills that claim to give you harder, longer-lasting erections without a prescription. But if it sounds too good to be true, it probably is.
Like other gas station sex pills with cool names and exotic ingredients, this product isn’t safe for use.
If you’re dealing with an issue like erectile dysfunction (ED) or premature ejaculation (PE), talking about it with a healthcare provider can be uncomfortable. That’s why — understandably — some men buy products like Stree Overlord, which is easily accessible from the local bodega or corner store.
We’ll discuss Stree Overlord and what science says about it. We’ll also share the risks of using this product and others like it before going over safer, research-backed, FDA-approved alternatives.
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The potential risks of using Stree Overlord outweigh the benefits of not having to make direct eye contact with a healthcare professional. Prescription drugs for ED and PE are approved by the U.S. Food and Drug Administration (FDA) and thoroughly tested to ensure their safety.
But, Stree Overlord? It may contain hidden drug ingredients and undeclared substances that pose a risk to your health.
Stree Overlord is a dietary supplement promoted as a sexual enhancement product, typically for men. It’s produced and distributed by a Japanese company called Mayo Kaisha Pharmacy Export, though information about the manufacturer and the product itself is hard to find.
The internet offers scarce returns when searching for it. We can’t find much more than a questionable podcast that may or may not be related and a few other references to Stree Overlord, none of which could point to a brand website.
This lack of information makes it very difficult to address things like medical claims (or a lack thereof) that might suggest how this product is supposed to be consumed.
The only “official” reference we found was an FDA press release warning about the dangers of Stree Overlord. According to the agency, the product was found to illegally contain sildenafil and ciprofloxacin — two prescription medications used in the treatment of erectile dysfunction and bacterial infections, respectively.
To be clear, neither of these ingredients is supposed to be in an over-the-counter supplement (which makes each one an undeclared ingredient) — and certainly not without appearing on the active ingredients list.
The FDA’s photo of the Stree Overlord packaging showed a claim to “exceed Vigra and Cialis®,” which we suspect is a typo — they probably meant Viagra®.
No worries — typos happen. It’s just a small error, but it probably shouldn’t be made by folks handling prescription erectile medications.
Based on what we know about dietary supplements sold in the U.S., products like Stree Overlord are not regulated like prescription and OTC medications. So, when you purchase these types of products, you can’t always be sure of what you’re taking and how it’ll impact your health.
We were able to find one ingredients list for Stree Overlord from an international seller we couldn’t vet. The online retailer listed Stree Overlord ingredients as:
Catuaba bark extract
Epimedium leaf extract
Cuscuta seed extract
Ginkgo biloba leaf
Muira puama bark extract
Hawthorn
Only a few of these ingredients have any research study data at all. Of those, hardly any have data showing any significant value in erectile function or “penis growth” arenas of medicine.
Only limited testing (and sometimes only animal testing) has supported claims that some of the exotic herbs on that list (like muira puama extract and saw palmetto) benefit erectile health.
Even if those results are replicated in other tests, scientists are years away from actually claiming to understand an effective dose of supplements based on these ingredients.
And that’s not even close to the bad part.
Here’s the thing about Stree Overlord: According to that 2020 press release we mentioned above, the FDA examined an import of the supplement and found that — in addition to the ingredients described by the company that produced it — it also contained things it wasn’t supposed to.
Of course, we’ve all heard horror stories about mystery meats and know about the potential dangers of additives. But what made the FDA’s claims against Stree Overlord so particularly bad was that Stree Overlord’s unlisted, potentially harmful ingredients were sildenafil and ciprofloxacin.
What’s more, a Stree Overlord review by the Australian Government found an undeclared amount of the antibiotic chloramphenicol.
Sildenafil has a number of potential side effects, including:
Nausea
Dizziness
Rash
Headaches
Flushing
Sudden hearing loss
Permanent damage to penile tissue
Low blood pressure (especially if taken with nitrates)
Ciprofloxacin, meanwhile, might cause nausea, diarrhea, and sensitivity to light. More severe adverse effects are also possible, like the risk of aortic aneurysm, tendonitis, and tendon rupture.
Chloramphenicol, which typically treats bacterial eye infections, can also cause serious side effects, such as fatal aplastic anemia (when the body can’t produce new blood cells), bone marrow suppression, and optic neuritis (swelling of the optic nerve).
All of this from ingredients that weren’t supposed to be there in the first place.
We need to clear up some confusion here. Sildenafil is the active ingredient in Viagra, which is one of the most effective and popularly prescribed ED medications in the world.
The difference between sildenafil in a Stree Overlord pill and a Viagra tablet is huge. Viagra is a carefully manufactured, regulated, and meticulously prescribed medication. When you buy it from a pharmacy, you know just how much sildenafil you’re taking, and you can follow your provider’s prescription instructions to the T.
With Stree Overlord (or any of the other gas station sex supplements containing sildenafil), there’s no telling how much sildenafil is in each pill. It could be 20 milligrams (generally okay for most people), but it could also be 200 milligrams (not okay for anyone).
See the difference?
At this point, our stance (in line with many scientists and healthcare experts) on products like Stree Overlord should be pretty clear: Don’t risk it and go with what research supports and what experts recommend.
What do experts recommend? Well, that depends on the sort of treatment you’re looking for.
Currently, the FDA has approved four medications to treat the symptoms of erectile dysfunction. They include:
Viagra (active ingredient sildenafil)
Stendra® (avanafil)
Levitra® (vardenafil)
These medications all belong to a class of medications called PDE5 inhibitors (short for phosphodiesterase-5 inhibitors). These drugs dilate blood vessels to increase blood flow to your penis.
Medications will probably be the first thing your healthcare provider recommends because they treat the immediate symptoms of ED quickly and efficiently.
Even as effective as ED medications are, your healthcare provider will probably try to help you get to the bottom of why you’re experiencing ED to begin with. Treating the symptoms is great, but attacking the underlying issue is more effective in the long term.
Many long-term erectile dysfunction treatments involve making healthy lifestyle changes. Taking better care of your body holistically can make a world of difference when you’re dealing with ED.
Some lifestyle adjustments your provider will address include:
Reducing stress
Exercising regularly
Eating a balanced diet
Cutting back on things like alcohol, nicotine, and other drugs
Getting proper rest
Maintaining a healthy weight
Checking testosterone levels
Cutting down on porn and masturbation
Communicating with your partner
You can take a sort of “trickle-down” approach to your health. What’s good for you in a general way will usually trickle down to being good for you in smaller ways — like in the bedroom.
Stree Overlord and other over-the-counter supplements are a shortcut. We’re not saying they or their ingredients won’t work. But the truth is, most men picking up potentially dubious supplements at gas stations are likely doing so to avoid an uncomfortable conversation with a healthcare professional.
Here’s a recap of our Stree Overlord review:
Stree Overlord is known to contain hidden ingredients like sildenafil. Though sildenafil is the active ingredient in Viagra, a well-studied ED medication, the sildenafil in Stree Overlord isn’t regulated. This means we don’t know how much it contains or how pure the ingredients are.
When you take undeclared amounts of sildenafil and other prescription drugs, you can experience harmful side effects. These side effects may include something as mild as nausea or something as serious as dangerously low blood pressure (hypotension).
There are other proven options available. Your liquor store clerk isn’t a physician. Skip the shortcuts and talk to a licensed healthcare provider to access a safe and effective treatment plan for your needs.
Health concerns and problems with sexual arousal aren’t something you should treat with undeclared sildenafil or herbal ingredients. The good news is that in the age of telehealth, you may not need to meet with a medical provider in person.
Ready to talk to a healthcare professional? Do a quick online consultation today to find out what ED medications are available and what other sexual health resources can help.
This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.
Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!
Dr. Kelly Brown is a board certified Urologist and fellowship trained in Andrology. She is an accomplished men’s health expert with a robust background in healthcare innovation, clinical medicine, and academic research. Dr. Brown was previously Medical Director of a male fertility startup where she lead strategy and design of their digital health platform, an innovative education and telehealth model for delivering expert male fertility care.
She completed her undergraduate studies at University of North Carolina at Chapel Hill (go Heels!) with a Bachelor of Science in Radiologic Science and a Minor in Chemistry. She took a position at University of California Los Angeles as a radiologic technologist in the department of Interventional Cardiology, further solidifying her passion for medicine. She also pursued the unique opportunity to lead departmental design and operational development at the Ronald Reagan UCLA Medical Center, sparking her passion for the business of healthcare.
Dr. Brown then went on to obtain her doctorate in medicine from the prestigious Northwestern University - Feinberg School of Medicine and Masters in Business Administration from Northwestern University - Kellogg School of Management, with a concentration in Healthcare Management. During her surgical residency in Urology at University of California San Francisco, she utilized her research year to focus on innovations in telemedicine and then served as chief resident with significant contributions to clinical quality improvement. Dr. Brown then completed her Andrology Fellowship at Medical College of Wisconsin, furthering her expertise in male fertility, microsurgery, and sexual function.
Her dedication to caring for patients with compassion, understanding, as well as a unique ability to make guys instantly comfortable discussing anything from sex to sperm makes her a renowned clinician. In addition, her passion for innovation in healthcare combined with her business acumen makes her a formidable leader in the field of men’s health.
Dr. Brown is an avid adventurer; summiting Mount Kilimanjaro in Tanzania (twice!) and hiking the incredible Torres del Paine Trek in Patagonia, Chile. She deeply appreciates new challenges and diverse cultures on her travels. She lives in Denver with her husband, two children, and beloved Bernese Mountain Dog. You can find Dr. Brown on LinkedIn for more information.
Education & Training
Andrology Fellowship, Medical College of Wisconsin
Urology Residency, University of California San Francisco
M.D. Northwestern University Feinberg School of MedicineB.S. in Radiologic Science, Chemistry Minor, University of North Carolina at Chapel Hill
Published as Kelly Walker
Cowan, B, Walker, K., Rodgers, K., Agyemang, J. (2023). Hormonal Management Improves Semen Analysis Parameters in Men with Abnormal Concentration, Motility, and/or Morphology. Fertility and Sterility, Volume 118, Issue 5, e4. https://www.sciencedirect.com/journal/fertility-and-sterility/vol/120/issue/1/suppl/S
Walker, K., Gogoj, A., Honig, S., Sandlow, J. (2021). What’s New in Male Contraception? AUA Update Series, Volume 40. https://auau.auanet.org/content/update-series-2021-lesson-27-what%E2%80%99s-new-male-contraception
Walker, K., Shindel, A. (2019). AUA Erectile Dysfunction Guideline. AUA Update Series, Volume 38. https://auau.auanet.org/content/course-307
Walker, K., Ramstein, J., & Smith, J. (2019). Regret Regarding Fertility Preservation Decisions Among Male Cancer Patients. The Journal of Urology, 201(Supplement 4), e680-e681. https://www.auajournals.org/doi/10.1097/01.JU.0000556300.18991.8e
Walker, K., & Smith, J. (2019). Feasibility Study of Video Telehealth Clinic Visits in Urology. The Journal of Urology, 201(Supplement 4), e545-e545. https://www.auajournals.org/doi/10.1097/01.JU.0000556071.60611.37