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Atorvastatin Side Effects Erectile Dysfunction: What to Know

Kelly Brown MD, MBA

Reviewed by Kelly Brown MD, MBA

Written by Geoffrey C. Whittaker

Updated 02/26/2025

Statins help people with high cholesterol manage their risk of heart disease and heart attack, but some worry these blood pressure medications can trigger erectile dysfunction (ED). Let’s just say you’re far from the first person to Google “atorvastatin side effects erectile dysfunction.”

Is atorvastatin erectile dysfunction a thing? And if so, why does atorvastatin cause ED?

When it comes to statins and ED, the connection isn’t necessarily something you need to fear. In fact, there might even be benefits of statins for sexual function.

To understand how statins and your sex life are intertwined, let’s first unpack how statins function and the penile and erectile consequences of that.

Statins (such as atorvastatin) help those with high cholesterol (hypercholesterolemia) manage lipid levels (specifically low-density lipoprotein or LDLs) and, therefore, manage elevated cholesterol levels.

This can reduce the risk of serious cardiology issues and events later in life like:

  • Heart attack

  • Stroke

  • Atherosclerosis (cholesterol and fat buildup in the arteries)

Statins are basically liver-modifying drugs. They tell your liver how to process cholesterol differently, specifically by inhibiting the function of an enzyme known as hydroxymethylglutaryl-CoA reductase (HMG-CoA).

By inhibiting this enzyme, your liver is told to produce less cholesterol overall and process existing cholesterol out of your body faster. This is a healthy method of lowering cholesterol levels.

Common generic statins and brand names include:

  • Simvastatin (Zocor®)

  • Rosuvastatin (Crestor®)

  • Pravastatin (Pravachol®)

  • Atorvastatin (Lipitor®)

All of these drugs require a prescription.

Atorvastatin doesn’t directly affect erectile health, according to research. However, it may indirectly affect it — and might actually improve your erections over time.

Aside from the psychological causes of erectile dysfunction, the most common causes of ED tend to be heart disease, blood pressure conditions, obesity, and other health problems.

The key trend among these causes is that they’re commonly associated with patients who might need statins. And they’re high on the list of problems that, when unaddressed, can cause ED later (or sooner) in life.

So high cholesterol and other medical issues statins are designed to treat are actually risk factors for erectile dysfunction, especially as men age.

While statins may not be a direct treatment for ED, they can help people with certain causes of ED reduce their symptoms.

Is one of the atorvastatin side effects erectile dysfunction? No, but keep reading for insight.

It’s unlikely that statins cause erectile dysfunction. There’s very little evidence that they cause ED, and the FDA-confirmed side effects of statins from clinical trials and statin therapy don’t include erection issues.

In fact, statins like atorvastatin may actually lead to long-term improvements in erectile function.

What’s the best statin for erectile dysfunction? That’s unclear. But a 2019 systematic review and meta-analysis from the World Journal of Men’s Health stated that statins may actually improve erectile function because they achieve several end goals that can boost erectile health.

Namely, statins might:

  • Improve endothelial function to keep blood running smoothly through the body, which supports erectile function

  • Increase the availability of nitric oxide, a crucial element in erections

  • Decrease oxidative stress on erectile tissues

That same meta-analysis, however, mentioned that there’s a chance statins may impair erections. As noted, one of the functions of statins is blocking the HMG-CoA enzyme, which could theoretically decrease testosterone (which itself promotes proper erectile function).

Fortunately, substantive evidence of statins causing low testosterone or ED hasn’t been published.

Statins usually aren’t prescribed to treat erectile dysfunction. That said, statins can address some of the underlying issues linked to ED. So you could see improvements in erectile issues as an indirect result of the other health problems the medication treats.

In other words, as part of a treatment plan, statins might be on the list of things that make your sexual function healthier.

When it comes to questions about your individual circumstances, speaking with a healthcare professional is always a wise choice. Someone with knowledge of your unique issues and health history can help you navigate statin use and erectile concerns and offer personalized medical advice.

As for official treatments for ED, they fall into three major categories: lifestyle changes, therapy, and medication.

Lifestyle Changes for ED

Research has long linked poor health (unhealthy eating, no exercise, lots of smoking, frequent drinking, etc.) to erectile problems. If we zoom out from a blood vessel in your penis to the larger portrait of sexual health and circulatory health, everything is connected.

Cardiovascular disease and sexual dysfunction are deeply linked. So when you prevent coronary heart disease, you may also see an improvement of erectile function.

These daily habits and lifestyle changes may help with both:

Remember, small changes can make a big difference in sexual health and overall health.

Therapy for ED

We should point out that while some patients with ED struggle with physiological issues (relating to normal bodily functioning), others may have erectile dysfunction problems due to psychological issues like low self-esteem, fear of intimacy, and performance anxiety.

Those mental roadblocks are best treated with therapy. Talk therapy can help you work through negative thought patterns to correct your usual way of approaching intimacy — and get healthy erections back in the game.

One of the best, most practical approaches to erectile dysfunction therapy is cognitive behavioral therapy (CBT). With this approach, you learn to reject negative, intrusive thoughts that may be causing anxiety or harming your self-esteem.

With time and practice, you can learn to master those thoughts and take back control of what’s going on in your head. CBT may leave you better prepared to focus on a healthy sex life.

Medication for ED

Medication for erectile dysfunction most commonly takes the form of PDE5 inhibitors. Short for phosphodiesterase type 5 inhibitors, these prescription drugs make blood flow to your penis easier and help your penis function to solidify and maintain erections.

You’ve likely heard of a couple of these medications already.

Sildenafil (the generic version of Viagra®) is a PDE5 inhibitor that can be taken before your planned romantic activities to give you the support you need.

Then there’s tadalafil (generic Cialis®), which can be taken as an as-needed ED medication or a once-daily prescription to help men get and maintain erections.

There are no known interactions between PDE5s and statins. Still, talk to a healthcare professional about the risks of a negative response to sildenafil or other medications just to be safe.

Sexual medicine becomes more complicated with age. Levels of the sex hormone testosterone can fall, and low testosterone can cause erectile dysfunction, high blood pressure, and heart disease. Sometimes, the medications you take to treat these problems can affect your erectile function too.

Cardiovascular risk factors, coronary artery disease, and other heart and blood flow problems can adversely affect patients with erectile dysfunction.

Here’s the bottom line on atorvastatin side effects and erectile dysfunction:

  • The atorvastatin and erectile dysfunction relationship is complicated. Statin treatment may yield benefits for some ED sufferers and create complications for others.

  • While it’s relatively uncommon to see more ED problems as a result of statin use, it’s nevertheless a (rare) possibility.

  • Always keep taking statins as directed. Overall health is about living your longest, most meaningful life.

Finding the right medication combinations for your best quality of life is something you should do carefully and deliberately — and with professional support.

If you’re ready, we can offer that professional support today. Get started with our free sexual health quiz.

4 Sources

  1. Chand SP, et al. (2022). Cognitive behavior therapy. https://www.ncbi.nlm.nih.gov/books/NBK470241/
  2. Kostis JB, et al. (2018). Statins and erectile dysfunction. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305857/
  3. Sizar O, et al. (2022). Statin medications. https://www.ncbi.nlm.nih.gov/books/NBK430940/
  4. Sooriyamoorthy T. (2023). Erectile dysfunction. https://www.ncbi.nlm.nih.gov/books/NBK562253/
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Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.

Kelly Brown MD, MBA
Kelly Brown MD, MBA

Dr. Kelly Brown is a board certified Urologist and fellowship trained in Andrology. She is an accomplished men’s health expert with a robust background in healthcare innovation, clinical medicine, and academic research. Dr. Brown was previously Medical Director of a male fertility startup where she lead strategy and design of their digital health platform, an innovative education and telehealth model for delivering expert male fertility care.

She completed her undergraduate studies at University of North Carolina at Chapel Hill (go Heels!) with a Bachelor of Science in Radiologic Science and a Minor in Chemistry. She took a position at University of California Los Angeles as a radiologic technologist in the department of Interventional Cardiology, further solidifying her passion for medicine. She also pursued the unique opportunity to lead departmental design and operational development at the Ronald Reagan UCLA Medical Center, sparking her passion for the business of healthcare.

Dr. Brown then went on to obtain her doctorate in medicine from the prestigious Northwestern University - Feinberg School of Medicine and Masters in Business Administration from Northwestern University - Kellogg School of Management, with a concentration in Healthcare Management. During her surgical residency in Urology at University of California San Francisco, she utilized her research year to focus on innovations in telemedicine and then served as chief resident with significant contributions to clinical quality improvement. Dr. Brown then completed her Andrology Fellowship at Medical College of Wisconsin, furthering her expertise in male fertility, microsurgery, and sexual function.

Her dedication to caring for patients with compassion, understanding, as well as a unique ability to make guys instantly comfortable discussing anything from sex to sperm makes her a renowned clinician. In addition, her passion for innovation in healthcare combined with her business acumen makes her a formidable leader in the field of men’s health.

Dr. Brown is an avid adventurer; summiting Mount Kilimanjaro in Tanzania (twice!) and hiking the incredible Torres del Paine Trek in Patagonia, Chile. She deeply appreciates new challenges and diverse cultures on her travels. She lives in Denver with her husband, two children, and beloved Bernese Mountain Dog. You can find Dr. Brown on LinkedIn for more information.

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