Lipogaine Review: Are These Minoxidil Products Worth It?

If you’ve been hunting for Lipogaine reviews to figure out whether this hair loss treatment actually works, you’re in the right place. With so many products promising results, it’s tough to know what’s worth your time (and money).

Lipogaine is a popular brand that uses medical-grade ingredients in its topical hair loss formulas. 

In this review, we’ll break down how it works, its ingredients, and how it compares to Rogaine. Plus, board-certified dermatologist Knox Beasley, MD, weighs in with his expert opinion.

Lipogaine is a brand that offers hair loss products made with proven ingredients like minoxidil, biotin, caffeine, and saw palmetto. The products are formulated to help anyone dealing with thinning hair.

A few examples of Lipogaine products include:

• Lipogaine for Men. A topical hair loss treatment that contains 5% minoxidil, biotin, saw palmetto, and ketoconazole.

• Lipogaine for Men (Sensitive). Same as the original formula but without propylene glycol, making it gentler for sensitive scalps. 

• Lipogaine Big 5 Shampoo. A DHT-blocker hair loss shampoo that contains caffeine, biotin, argan oil, castor oil, and saw palmetto.

These products claim to tackle hair thinning and male pattern baldness from multiple angles, but do they actually work? Let’s take a look at the science.

The main active ingredient in Lipogaine is minoxidil, an FDA-approved topical medication that increases blood flow to the scalp and extends the hair growth phase (anagen).

Clinical studies show that 5% minoxidil can help with hair regrowth and slow down hair loss in men with androgenetic alopecia (male pattern baldness).

Lipogaine also contains the following hair-friendly ingredients:

• Saw Palmetto. May help block dihydrotestosterone (DHT), a hormone linked to male pattern hair loss. While research is still emerging, some studies suggest it may reduce hair shedding.

• Caffeine. Studies show it could help stimulate hair follicle growth and fight the effects of DHT.

• Biotin. It might help support hair health if you’re deficient in it, but there’s limited evidence to show it can boost hair growth.

• Ketoconazole (in some formulations). An antifungal that may help calm inflammation and support a healthier scalp.

How to Use Lipogaine

Here’s a quick rundown of how to apply Lipogaine.

• Topical solution: Apply twice daily.

• Shampoo: Use it 3–4 times per week.

Most people start seeing results around 3 to 6 months, but results vary from person to person.

Below, our medical expert, Dr. Knox Beasley, shares his insight on Lipogaine products.

Lipogaine for Men Review

Product type: Topical solution

Key ingredients: Minoxidil

Cost: $30 per 2-oz bottle

Purpose: To help stimulate hair growth

• Efficacy: ★★★★ ”This also has a DHT blend of different ingredients, which has limited data but may be helpful for hair loss in addition,” says Dr. Beasley.

• Side effects: ★★★★ “Minoxidil is generally very tolerated. This does have propylene glycol, which could potentially cause local skin irritation. However, they do have a propylene glycol-free formula,” he adds.

• Ease of use: ★★★★

Lipogaine for Men (Sensitive) Review

Product type: Topical solution

Key ingredients: Minoxidil

Cost: $34.95 per 2-oz bottle

Purpose: To help stimulate hair growth

• Efficacy: ★★★★

• Side effects: ★★★★ “This does not have propylene glycol, so it may be less irritating to the scalp,” says Dr. Beasley.

• Ease of use: ★★★★

Lipogaine Big 5 Shampoo Review

Product type: Hair growth shampoo

Key ingredients: Ketoconazole, biotin, caffeine, argan oil,  and castor oil 

Cost: $29.95 per 8-oz bottle

Purpose: To help stimulate hair growth

• Efficacy: ★★ “This has ketoconazole in it, which may potentially help with hair loss, but data is limited,” says Dr. Beasley.

• Side effects: ★★★★★

• Ease of use: ★★★★★

Pros

• Contains 5% minoxidil, an FDA-approved hair loss treatment

• Blends multiple ingredients that support hair and scalp health

• Offers a gentle formula for those with sensitive scalps

• Available in both shampoo and topical solution options

• May support both scalp health and encourage hair growth

• Can be used with other hair loss treatments

Cons

• May cause temporary shedding when you first start using it

• Some users may experience dryness or irritation

• Needs consistent use to produce results

Does Lipogaine Work?

Lipogaine contains 5% minoxidil, a proven, FDA-approved treatment for hair loss due to male pattern baldness. Just be sure to use it consistently and as directed for the best results.

How Long Until I See Results with Lipogaine?

Hair growth takes time, so give it 3 to 6 months of regular use. You may notice some shedding early on — that’s a normal part of the process.

Is Lipogaine Safe?

Minoxidil products are generally safe for most people. But always patch test first to look for redness, flaking, inflammation, or itchiness. 

If you have sensitive skin, Lipogaine offers a gentler formula without propylene glycol, a common irritant.

Can I Use Lipogaine with Other Hair Loss Treatments?

Yes. You can use Lipogaine with oral finasteride or supplements like biotin. Just check with a dermatologist before combining medications or supplements.

Need help? Hims can connect you to a licensed provider who can create a personalized hair loss treatment plan for you.

Both Lipogaine and Rogaine contain 5% minoxidil to help with hair growth.

Rogaine is a well-known hair loss brand and is available in both liquid and foam solutions, containing only minoxidil.

Lipogaine contains added ingredients like saw palmetto, caffeine, and biotin to support scalp and hair follicle health.

“The key ingredient in both Rogaine and Lipogaine is minoxidil, a proven treatment for male pattern hair loss. Rogaine is easy to find over the counter, while Lipogaine offers extra ingredients for those looking for a little more. Just keep in mind, the evidence for those added ingredients is limited,” says Dr. Beasley.

Lipogaine pricing varies depending on the product and bundle, but you can expect to pay around $30–$35 for a two-ounce supply of the topical solution. 

The Big 5 Shampoo typically costs around $29.95 per eight-ounce bottle. 

Like all hair loss treatments, Lipogaine can cause side effects. These may include:

• Scalp dryness or flaking

• Redness or irritation

• Temporary hair shedding (usually within the first month)

• Allergic reactions (rare)

The Sensitive formula is a good choice for those with a history of scalp irritation. If you experience persistent or severe side effects, stop using the product and reach out to a healthcare provider. 

Looking for other options besides Lipogaine? Here are a few proven hair loss treatment alternatives.

Minoxidil

Minoxidil is a proven treatment for male pattern hair loss. It increases blood flow to the scalp and helps keep hair in its growth phase longer. You can find it over the counter in foam or liquid form.

Finasteride

Finasteride is a prescription pill that blocks DHT, the hormone behind most hair loss in men. People often use it along with minoxidil for better results.

Our Topical Finasteride & Minoxidil Spray makes it easy to apply both ingredients.

DHT-Blocking Shampoos

For mild thinning, a DHT-blocking shampoo — like Hims Thick Fix Thickening Shampoo  with saw palmetto — may help.

These shampoos support scalp health, but work best when combined with other treatments for more noticeable hair loss.

Let’s recap what we know about Lipogaine:

• Lipogaine products contain minoxidil. Minoxidil is clinically proven to support hair regrowth.

• They also contain other ingredients. Other hair-friendly ingredients like saw palmetto and caffeine may offer extra hair benefits.

• The topical solution is available in standard and sensitive versions. If you have skin sensitivities, you can opt for the brand’s sensitive formula without propylene glycol, which can cause irritation in some people.

• Lipogaine shampoo can help maintain scalp health. But it won’t reverse hair loss on its own.

If you’re searching for an effective hair loss treatment, Hims can connect you with a provider to help you find the best option for your needs.