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Can Viagra Cause a Heart Attack?

Mike Bohl, MD, MPH, ALM

Reviewed by Mike Bohl, MD, MPH, ALM

Written by Geoffrey C. Whittaker

Published 03/08/2021

Updated 04/06/2024

Viagra® is widely considered safe when used properly. In fact, tens of millions of men all over the world use it to treat the symptoms of erectile dysfunction (ED) every year. While you may have heard stories that ED meds can make existing heart disease worse or even cause heart attacks, we’re here to tell you that they’re (mostly) incorrect.

Erectile dysfunction medication has a direct impact on your cardiovascular system. Drugs like Viagra cause vasodilation, meaning they work by relaxing smooth muscles in arteries. Doing so doesn’t normally trigger a heart attack or other heart health problems. But, if taken incorrectly or in combination with certain other drugs, it could cause blood pressure issues and increase your risk and severity of certain side effects.

Below, we’ve delved into the subject of Viagra and its effect on your heart in more detail, because as you’ve probably already realized, this is a complex topic.

During postmarketing surveillance (which takes place after a drug has been FDA approved), heart attacks that have a temporal association with the use of Viagra have been seen in some people. However, it isn’t possible to determine if heart attacks are actually due to Viagra or due to something else (like sexual activity), and it also isn’t possible to know how common this is. That said, if you take certain medications that aren’t meant to be combined with Viagra, it could pose heart-related health risks.

A heart attack, also known as a myocardial infarction, occurs when blood flow to part of the heart muscle is reduced or interrupted. Some of the most common symptoms of heart attack include chest pain, weakness, shortness of breath and pain or discomfort in the back, arms or shoulders. 

In most cases, a heart attack is the result of atherosclerosis — the narrowing of the arteries caused by the buildup of fat, cholesterol and other substances. The arteries supplying blood to the heart become narrowed or closed off, reducing blood flow to the heart. 

You’re probably asking “Is Viagra a vasodilator” expecting us to say that if it is, Viagra should probably prevent heart disease, right?

Viagra — and its main ingredient, sildenafil citrate — can lower blood pressure. If used in combination with certain other medications that lower blood pressure, it’s possible to get dangerously low blood pressure. This could, in theory, result in less blood flow to the heart.

This isn’t the only potential link between ED medication use and heart health: guys taking medications like Levita®, Cialis® or Viagra tend to return to vigorous activity. 

Experts cite the results of a 2002 study published in the journal, JAMA, to support the theory that heart attacks linked to Viagra were potentially related to the performance of sexual activity (specifically in patients with coronary artery disease) than to the use of the drug.

The Link Between Heart Disease and ED

Speaking of heart disease and sexual activity, it’s important to note that there is a link between erectile dysfunction and heart disease

Erectile dysfunction can sometimes serve as a warning sign for men with underlying heart conditions.

This is because both erectile dysfunction and many cardiovascular issues (heart attack, chest pain or angina, strokes, and other conditions) can be caused by the same issue — atherosclerosis

Like we said before, atherosclerosis happens when arteries narrow due to fat and cholesterol buildup, causing the arteries to fail at serving as a vessel for blood flow. If blood can’t sufficiently reach the heart —or the penis — you can run into health episodes. 

If you’re experiencing erectile dysfunction, there could also be underlying heart issues to talk to your healthcare provider about.

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Because erectile dysfunction and heart conditions are linked, it’s important to consider the link between erectile dysfunction treatment and heart conditions. The concern is the drug’s effect on the arteries.

Whether Viagra is safe for men with heart disease depends on the individual. For many men with heart disease, a drop in blood pressure of up to 8.3/5.3 mmHg wouldn’t be considered dangerous. 

For certain heart conditions, however, it could be. This may be the case for severe heart failure, aortic stenosis and more.

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Like other prescription medications, there is a risk of side effects from Viagra. These are generally mild and temporary, though interactions with other prescription medications can be serious.

For instance, because Viagra was originally developed as a treatment for pulmonary hypertension, it may interact poorly with other heart medications. 

Men taking nitrates and guanylate cyclase stimulators should not take Viagra.

Nitrates are typically prescribed for angina (chest pain) and guanylate cyclase stimulators like Adempas® (generic riociguat) are prescribed for pulmonary hypertension. 

Pairing Viagra with these medications may cause your blood pressure to drop to an unsafe level. 

However, even for men not taking nitrates, there has been some concern surrounding whether Viagra might make underlying heart conditions worse. 

Given the known interactions between Viagra and heart medications, the FDA has urged caution in patients who have experienced heart attack, stroke or other serious cardiovascular events within six months. 

Men with a history of congestive heart failure, low blood pressure or uncontrolled high blood pressure should exercise caution, too.

ED Treatment

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Talk to your healthcare provider about the potential risks before taking Viagra. Make sure to tell them about any medication, both prescription and non-prescription, you may be taking, and about any underlying health conditions you have. 

For more information about Viagra (sildenafil) warnings, check out our blog.

You might also want to read our guide to the most common ED treatments before seeking medical advice from your healthcare provider so you understand the options.

1 Source

  1. Adelaide M. Arruda-Olson, M. D. (2002, February 13). Cardiovascular effects of sildenafil during exercise in men with known or probable coronary artery disease. JAMA. Retrieved January 11, 2022, from https://jamanetwork.com/journals/jama/fullarticle/194635
Editorial Standards

Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.

Mike Bohl, MD, MPH, ALM

Dr. Mike Bohl is a licensed physician and the Director of Medical Content & Authority at Hims & Hers. Prior to joining Hims & Hers, Dr. Bohl worked in digital health at Ro, focusing on patient education, and as the Director of Scientific & Medical Content at a stealth biotech PBC, working on pharmaceutical drug development. He has also worked in medical journalism for The Dr. Oz Show (receiving recognition for contributions from the National Academy of Television Arts and Sciences when the show won Outstanding Informative Talk Show at the 2016–2017 Daytime Emmy® Awards) and at Sharecare, and he is a Medical Expert Board Member at Eat This, Not That!.

Dr. Bohl obtained his Bachelor of Arts and Doctor of Medicine from Brown University, his Master of Business Administration and Master of Science in Healthcare Leadership from Cornell University, his Master of Public Health from Columbia University, and his Master of Liberal Arts in Extension Studies—Journalism from Harvard University. Dr. Bohl trained in internal medicine with a focus on community health at NYU Langone Health.

Dr. Bohl is Certified in Public Health by the National Board of Public Health Examiners, Medical Writer Certified by the American Medical Writers Association, a certified Editor in the Life Sciences by the Board of Editors in the Life Sciences, a Certified Personal Trainer and Certified Nutrition Coach by the National Academy of Sports Medicine, and a Board Certified Medical Affairs Specialist by the Accreditation Council for Medical Affairs. He has graduate certificates in Digital Storytelling and Marketing Management & Digital Strategy from Harvard Extension School and certificates in Business Law and Corporate Governance from Cornell Law School.

In addition to his written work, Dr. Bohl has experience creating medical segments for radio and producing patient education videos. He has also spent time conducting orthopaedic and biomaterial research at Case Western Reserve University and University Hospitals of Cleveland and practicing clinically as a general practitioner on international medical aid projects with Medical Ministry International.

Dr. Bohl lives in Manhattan and enjoys biking, resistance training, sailing, scuba diving, skiing, tennis, and traveling. You can find Dr. Bohl on LinkedIn for more information.

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