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Can Biotin Cause Acne?

Knox Beasley, MD

Reviewed by Knox Beasley, MD

Written by Lauren Panoff

Published 10/04/2024

Biotin is an essential vitamin and a popular supplement, but can biotin cause acne? It’s possible, though it would be hard to say for sure whether it’s the actual cause.

Picture this: You’re getting ready for a date when you look in the mirror and discover an unsightly pimple emerging from your forehead. 

This has been happening more lately and you’re not sure why. Is it job stress, sweating it out at the gym, or the biotin supplement you started taking for your hair? Let’s focus on that last one.

Biotin (vitamin B7) is a water-soluble vitamin involved in converting food to energy, supporting nervous system health, and maintaining healthy skin, hair, and nails — which explains why it’s often found in skin and hair supplements

However, some people are concerned biotin may be making their acne worse. Does biotin help acne or cause it?

We’ll look at the relationship between biotin supplements and skin health, including whether they’re helpful or harmful for treating pesky pimples.

Biotin is an essential component of enzymes involved in metabolic processes like breaking down carbohydrates, fats, and proteins. It also helps your body convert food into energy to support growth and development.

Evidence suggests biotin is a key player in healthy nervous system function and normal blood sugar levels.

And some research indicates it’s important for regulating certain inflammatory responses in the body as well as immune functions, like the activity of white blood cells (which help your body fight germs).

Biotin deficiency is rare but possible. It might be influenced by a genetic defect or by not consuming enough food sources of this vitamin.

Some people have a higher risk of developing low biotin levels. This includes pregnant people and breastfeeding women, likely because of metabolism changes during pregnancy and lactation.

Possible signs that your body is lacking adequate amounts of biotin include

  • Brittle nails

  • Tiredness

  • Seizures

  • Changes in hair growth, like thinning hair or hair loss

  • Depression or low mood

  • Dry skin, especially a scaly red rash around the mouth, eyes, or nose

Fortunately, biotin is a widely available nutrient in foods like: 

  • Egg yolks

  • Nuts and seeds (think almonds, peanuts, and sunflower seeds)

  • Legumes (lentils, peas, and soybeans)

  • Whole grains (oats, barley, and wheat)

  • Organ meats (liver and kidney)

  • Fish (especially salmon and sardines)

  • Dairy products (milk, cheese, and yogurt)

  • Avocados

  • Mushrooms

  • Sweet potatoes

Still, lots of folks decide to add a biotin supplement to their routines, thinking it may support healthy skin. But biotin isn’t a standard first-line acne treatment recommended by most dermatologists.

Since acne is such a common skin complaint, there’s no shortage of acne treatments. We’re talking daily cleansers, ointments, cleansing pads, and oral supplements like biotin.

Because low biotin levels may lead to changes in your skin, hair, and nails, this nutrient is commonly thought to be important for their health and appearance. 

When biotin was discovered, it was originally called “vitamin H” after the German words “haar” and “haut,” respectively meaning “hair” and “skin.”

While evidence is limited, biotin supports the production of fatty acids that some researchers think nourish the skin and help maintain its hydration and smoothness. 

Therefore, having adequate biotin levels may help improve the barrier function of your skin, protecting it from the elements and reducing dryness and irritation.

See our blog for tips on building a skincare routine for men.

We get it: When your face breaks out, you’re on a mission to determine the culprit.

If you’ve been taking a biotin-containing supplement and are suddenly seeing pimples, you might assume the two are related.

Some people blame biotin for acne breakouts because high doses of biotin supplements may interfere with the absorption of other B vitamins — particularly vitamin B5 (pantothenic acid), which plays a role in maintaining healthy skin. 

When biotin levels increase, pantothenic acid levels may decrease, possibly triggering skin changes like acne. 

Beyond that, biotin might make the sebaceous (oil) glands in your skin produce more sebum. This could result in trapped skin cells that contribute to clogged pores and breakouts in those already prone to acne.

However, there’s not enough evidence to say biotin supplements directly contribute to the development or worsening of acne, and more research is needed. 

So, if you’re wondering how to avoid pimples when taking biotin, you can breathe a sigh of relief.

If you’re seeing more acne, many other factors may be involved, such as:

  • Hormonal changes 

  • Stress, which increases cortisol levels, leading to more oil production

  • Certain medications, like corticosteroids, antidepressants, and birth control pills

  • Dietary supplements like iodine, whey, and muscle-building products

  • Diet, particularly eating lots of refined sugars, dairy, or high-glycemic foods

  • Skincare products, including comedogenic (pore-clogging) formulas

  • Genetics

  • Environmental factors, such as pollution or excessive humidity

  • Over-cleansing or an aggressive skincare routine, which can irritate the skin and increase oil production

Can biotin cause acne? On the contrary, more research actually points to the benefits of biotin in treating acne.

Some studies suggest biotin can help treat comedonal acne and support clear skin. This type of acne typically manifests as blackheads and whiteheads on the chin and forehead.

Biotin supplements might also help alleviate red, flaky rashes and irritated skin caused by acne.

In a 12-week randomized controlled trial, researchers found that both a topical cream and an oral biotin-containing supplement significantly improved mild to moderate acne in adults. But it’s important to note that biotin wasn’t the only vitamin or ingredient used in the acne treatment.

This seems to be a fairly common conclusion in research. Many promising acne treatments contain biotin, but researchers are unable to say if improvements were from biotin alone.

There’s no standard guidance for how to treat acne with biotin or other B vitamins, given that the evidence is so sparse.

But biotin is present in many foods, along with other B vitamins and nutrients. 

It also doesn’t have a tolerable upper intake level (UL) — that’s the maximum daily amount of a nutrient that’s unlikely to cause harmful effects in most people, according to health authorities like the National Academy of Medicine.

This is because excess amounts of water-soluble vitamins are typically excreted in urine (you pee them out) rather than stored in the body, making toxicity from biotin supplementation rare.

Still, you don’t need to take high doses of biotin. While a large amount of biotin is unlikely to cause or worsen pimples and other skin conditions, it’s probably not going to help, either.

The best way to make sure you’re getting enough biotin is to eat a variety of biotin-rich foods. You can also take a multivitamin containing the recommended daily biotin intake of 30 micrograms (mcg).

If you’re experiencing blemishes, especially as a grown man, it’s understandable to look for a root cause and want to find a solution.

Can biotin cause acne? There’s not much research to support this, but it’s possible.

Here are some key points to remember when it comes to biotin and acne management:

  • Acne is multifactorial. Many things contribute to the health and appearance of your skin, including stress, hormonal changes, diet, and personal care products. Whether you’re taking biotin is unlikely to be the ultimate determining factor for developing acne.

  • Biotin may (or may not) help. There’s no definitive evidence that biotin directly causes or helps acne. Some research suggests it can support skin barrier function, while other experts think the relationship between biotin and vitamin B5 may play into skin changes that contribute to annoying zits. 

  • It’s worth a shot. Could it help? Maybe. Fortunately, supplemental biotin has a low risk for side effects and doesn’t have an established upper safety limit, so it may be worth a gamble.

  • Lots of foods contain biotin. This nutrient is also widely available in foods. You can ensure you’re getting the recommended daily amount by eating things like egg yolks, nuts, seeds, legumes, and avocados. Or consider taking a multivitamin.

Acne is annoying, but it doesn’t define you. If you’re concerned about breakouts or other skin changes, it’s best to see a dermatology specialist or another healthcare provider for proper examination, medical advice, and treatment options.

Ready to take a step toward healthier skin? Hims can help. Take our free online skin care assessment to get connected with a licensed healthcare professional and explore custom skincare prescriptions.

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.

13 Sources

  1. Aksac SE, et al. (2021) Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters. https://pubmed.ncbi.nlm.nih.gov/33682085/
  2. Güder H, et al. (2023). A retrospective evaluation of the laboratory findings of dermatology patients whose biotin levels were checked. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404308/
  3. Kuroishi T. (2015). Regulation of immunological and inflammatory functions by biotin. https://pubmed.ncbi.nlm.nih.gov/26168302/
  4. Lipner SR. (2020). Update on biotin therapy in dermatology: time for a change. https://pubmed.ncbi.nlm.nih.gov/33346513/
  5. Meixiong J, et al. (2022). Diet and acne: a systematic review. https://pubmed.ncbi.nlm.nih.gov/35373155/
  6. Office of Dietary Supplements (ODS). (2022). Biotin fact sheet for health professionals. https://ods.od.nih.gov/factsheets/Biotin-HealthProfessional/
  7. Piraccini BM, et al. (2019). Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea. https://pubmed.ncbi.nlm.nih.gov/31638351/
  8. Saleem F, et al. (2023). Biotin deficiency. https://www.ncbi.nlm.nih.gov/books/NBK547751/
  9. Tolino E, et al. (2018). Novel combination for the treatment of acne differentiated based on gender: a new step towards personalized treatment. https://pubmed.ncbi.nlm.nih.gov/29417793/
  10. Trüeb R. (2016). Serum biotin levels in women complaining of hair loss. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989391/
  11. Vaidya T, et al. (2024). Evaluating common ingredients contained in dietary acne supplements: an evidence-based review. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10941853/
  12. Zamil DH, et al. (2020). Acne related to dietary supplements. https://pubmed.ncbi.nlm.nih.gov/32941710/
  13. Zari S, et al. (2017). The association between stress and acne among female medical students in Jeddah, Saudi Arabia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722010/
Editorial Standards

Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.

Knox Beasley, MD

Dr. Knox Beasley is a board certified dermatologist specializing in hair loss. He completed his undergraduate studies at the United States Military Academy at West Point, NY, and subsequently attended medical school at Tulane University School of Medicine in New Orleans, LA. 

Dr. Beasley first began doing telemedicine during his dermatology residency in 2013 with the military, helping to diagnose dermatologic conditions in soldiers all over the world. 

Dr. Beasley is board certified by the American Board of Dermatology, and is a Fellow of the American Academy of Dermatology.

Originally from Nashville, TN, Dr. Beasley currently lives in North Carolina and enjoys spending time outdoors (with sunscreen of course) with his wife and two children in his spare time. 

Education

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  • Dermatology Residency. San Antonio Uniformed Services Health Education Consortium

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