What Happens If I Stop Taking Weight Loss Medication?

If you’ve been using a GLP-1 such as semaglutide, then you’ve likely experienced the powerful effects of this weight loss medication. You’re making smarter food choices, moving more, and achieving your health goals. Maybe you’ve even reached your goal weight. But what happens when you decide to stop taking semaglutide? 

Semaglutide, which is commonly used to manage type 2 diabetes, is intended for long-term use.  Side effects from doing so are rare. 

Ending a course of semaglutide isn’t just about putting the medication aside — it’s about ensuring a smooth transition that sets you up for long-term success. Here’s what you need to know about the process of stopping semaglutide, the potential risks, and how to do it safely.

Semaglutide works by mimicking a natural hormone in your body that regulates appetite and helps control blood sugar. When you stop taking it, these effects gradually fade. You might notice:

• Increased hunger. Without semaglutide, your appetite could return to its pre-treatment levels.

• Weight gain. If you don’t take steps to maintain your new healthy eating and activity habits, you might regain the weight you lost on semaglutide.

• Potential metabolic shifts. Your body might adjust how it processes food and manages energy, which can affect your weight and blood sugar levels.

Stopping semaglutide is a process that should always be done under the guidance of a healthcare provider. 

If you get semaglutide through Hers, you can connect with a healthcare provider on the app, and they will guide you through the tapering process. 

Here’s how to do it safely:

Follow a Tapering Plan

Stopping semaglutide abruptly might lead to uncomfortable side effects or a sudden return of appetite and cravings. Your provider may recommend gradually reducing your dose over time to help your body adjust. If you have any questions or negative side effects, you can reach out to a healthcare provider.

Focus on Healthy Habits

Lifestyle changes are key to maintaining your progress. While semaglutide may have helped you along the way, sustainable habits will carry you forward. Remember to:

• Eat balanced meals. Prioritize whole foods, lean protein, and fiber-rich options to keep you feeling full.

• Stay active. Regular physical activity helps maintain weight loss and supports overall health.

• Practice mindful eating. Tune in to your body’s hunger and fullness cues to avoid overeating.

Monitor Your Body

Pay attention to how you feel during the transition. If you notice significant changes in appetite, energy levels, or weight, share them with your provider so adjustments can be made.

Stay Patient and Positive

Some fluctuations in weight or appetite are normal as your body adapts. The key is to focus on the bigger picture — building and sustaining a healthy lifestyle over time.

Many people worry about weight regain after stopping semaglutide, and that’s understandable. The medication is an effective tool, but it’s only part of the equation. The habits you’ve developed while on semaglutide — like healthier eating patterns and consistent physical activity — are the foundation of long-term success.

If challenges arise, don’t hesitate to reach out to your healthcare team for support. There may be other strategies or tools to help you maintain your progress.

Stopping semaglutide doesn’t mean your journey is over — it means you’re taking the next step in managing your health and well-being. By approaching this transition thoughtfully and with the right support, you can continue to thrive.

Remember: The information provided here is NOT MEDICAL ADVICE and is for informational purposes only. Please consult your healthcare provider if you have questions or concerns. Always consult your healthcare provider before making changes to your medication regimen. If you’re taking semaglutide for reasons other than weight loss — such as for type 2 diabetes — be sure to work with your provider to determine other ways to control your blood sugar levels before stopping the medication.