Content
Over 90% of users saw increased regrowth or reduced hair loss in clinical trials
Today we have the honor of introducing you to a group of life-saving medications: vasodilators. These prescription meds can do things like prevent heart attacks and help give you firmer erections. Pretty neat stuff.
Blood flow is life, no blood flow is death and when it comes to your hair and your penis, the process of vasodilation (dilating your blood vessels) is almost as important. And consequently, in a roundabout way, vasodilators are equally important.
Below, we’ve covered:
What vasodilators are
The side effects of vasodilators
The most common types of vasodilators
Read on to learn more about what, how, why and when these meds can put help keep your health in check — both in and out of the bedroom.
Content
Today we have the honor of introducing you to a group of life-saving medications: vasodilators. These prescription meds can do things like prevent heart attacks and help give you firmer erections. Pretty neat stuff.
Blood flow is life, no blood flow is death and when it comes to your hair and your penis, the process of vasodilation (dilating your blood vessels) is almost as important. And consequently, in a roundabout way, vasodilators are equally important.
Below, we’ve covered:
What vasodilators are
The side effects of vasodilators
The most common types of vasodilators
Read on to learn more about what, how, why and when these meds can help keep your health in check — both in and out of the bedroom.
Vasodilators (sometimes called blood vessel dilators) work by helping the smooth muscle cells in the walls of your blood vessels relax so that blood flows through them more easily.
When your blood vessels dilate, blood flows through your whole body more efficiently. That means your organs, tissues and cells get more oxygen, which in turn keeps them healthy and operating normally. In the long term, it can help prevent things like heart disease.
There are several different vasodilators and each comes with different instruction manuals. Some directly affect specific muscles so that they relax, while others contain chemicals that interrupt reactions to expand all of your body’s blood vessels. Different types of vasodilators or blood pressure medications include:
Angiotensin-Converting Enzyme (ACE) Inhibitors: Angiotensin is a chemical that causes blood vessels to constrict. This direct vasodilator decreases angiotensin to open blood vessels.
Nitrates: Another direct vasodilator, nitrates (as in nitroglycerin) transform into nitrous oxide, which in turn helps open blood vessels.
Angiotensin Receptor Blockers (ARBs): This medication prevents angiotensin from attaching to your blood vessel walls. When this type of indirect vasodilator prevents this attachment, it allows blood vessels to open.
Calcium Channel Blockers (CCBs): Calcium helps arteries constrict. Calcium channel blockers like nifedipine prevent calcium from entering your artery walls, thereby helping them not constrict. This medication is known as a systemic vasodilator.
Vasodilators treat various conditions — most of them related to hypertensive issues. Some of the most common conditions that vasodilators are used to treat are:
High blood pressure (hypertension)
Congestive heart failure and myocardial infarction
Angina and Coronary Artery Disease
Pulmonary hypertension
Some of these even have specific uses like fighting hair loss (Minoxidil is one such type of vasodilator). This particular vasodilator can be taken orally (and is also used to treat high blood pressure), but can also be used in topical form to treat hair loss.
Some medications for ED are also considered vasodilators. Like a water balloon, your penis grows when a liquid — in this case, blood — flows in. In this awkward metaphor, erectile dysfunction results from the balloon not being able to fill properly. Vasodilators often solve the problem.
Vasodilators come with some pretty heavy side effects. Because of this, they’re usually only prescribed when nothing else has worked.
If your healthcare provider prescribes a vasodilator, you may need other medications to address some of the severe side effects. For example, it could cause extreme fluid retention (edema) and you may need a diuretic to help ease that.
The most serious side effect is arguably hypotension — the “hey I work in cardiology” term for low blood pressure. Lower blood pressure is good if you have vasoconstriction, but if it gets low enough your heart can just, you know, stop. So you should never take more of these than what’s prescribed to you.
Other common adverse effects connected to taking vasodilators include:
Fatigue
Joint pain
Headaches
Chest pain
Dizziness
Dry cough, especially when taking ACE inhibitors
Heart palpitations or increased heart rate
Nausea and/or vomiting
Along with side effects, you need to be careful of medication interactions when taking a vasodilator. For example, ACE inhibitors can react poorly with potassium supplements and medications with lithium. And nitrates can interact poorly with sildenafil and tadalafil.
Our point is that it’s always important to disclose any and all medications you are currently taking before you start taking something new.
You’ll want to tell your healthcare provider if you’re on beta blockers, nitric oxide, nitroprusside or other antihypertensive medications.
Arguably speaking, the most common vasodilators might be selective vasodilators like the ones used to treat erectile dysfunction and hair loss. They’re available through a variety of providers.
But those typically aren’t categorized alongside the ones we’ve been discussing.
Within the general category, though, ARBs and CCBs are the most common options used.
ARBs are commonly prescribed as indirect inhibitors. A popular ARB is losartan.
CCBs are also common — one that may be suggested to you is called diltiazem.
Natural vasodilators are a sticky subject. A variety of supplements not approved by the Food and Drug Administration (FDA) may make dubious claims that suggest they provide the same benefits as something like Viagra® with an “herbal” or “natural” ingredient list. Common examples include L-arginine, niacin and magnesium.
In many cases, these new age-y cousins of gas station sex pills are way less safe than just talking to a healthcare professional about prescribing you the real stuff.
Ironically, there’s another commonly used vasodilator that you may have used recently without knowing it — booze. While you probably associate alcohol with whiskey dick, alcohol is a natural vasodilator (it’s why people who drink to excess can look flushed).
If you’re looking for the safest and most universally recommended vasodilator on the market however, may we present our favorite: exercise.
Exercise can increase vasodilation and restore healthy blood flow to the body. It can also (along with a healthy diet) reduce obesity risk and other factors that can make it hard to, well, get hard
Vasodilators are most commonly used to treat heart conditions like congestive heart failure, vascular disease, high blood pressure and more.
There are different types of vasodilators. Direct vasodilators increase blood flow by affecting smooth muscles. Indirect vasodilators interrupt other activities that cause constriction.
ED medications can act as vasodilators for the tissues in your penis.
There’s even a topical vasodilator (topical minoxidil) that’s popularly used to treat hair loss in men.
Vasodilator medications do come with a risk of side effects — like nausea, increased heart rate and more.
Direct vasodilators tend to have more severe side effects and are not used quite as often. Indirect vasodilators tend to be prescribed a bit more often because the side effects are less pronounced. Vasodilators should never be used with medications for ED without a healthcare professional’s knowledge — crossing the two can be fatal.
If you think you may qualify for the administration of vasodilator medication, it’s best to schedule a consultation with a healthcare provider. They will be able to assess your condition and determine the appropriate treatment plan for you.
Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!
Dr. Knox Beasley is a board certified dermatologist specializing in hair loss. He completed his undergraduate studies at the United States Military Academy at West Point, NY, and subsequently attended medical school at Tulane University School of Medicine in New Orleans, LA.
Dr. Beasley first began doing telemedicine during his dermatology residency in 2013 with the military, helping to diagnose dermatologic conditions in soldiers all over the world.
Dr. Beasley is board certified by the American Board of Dermatology, and is a Fellow of the American Academy of Dermatology.
Originally from Nashville, TN, Dr. Beasley currently lives in North Carolina and enjoys spending time outdoors (with sunscreen of course) with his wife and two children in his spare time.
Bachelor of Science, Life Sciences. United States Military Academy.
Doctor of Medicine. Tulane University School of Medicine
Dermatology Residency. San Antonio Uniformed Services Health Education Consortium
Board Certified. American Board of Dermatology
Wilson, L. M., Beasley, K. J., Sorrells, T. C., & Johnson, V. V. (2017). Congenital neurocristic cutaneous hamartoma with poliosis: A case report. Journal of cutaneous pathology, 44(11), 974–977. https://onlinelibrary.wiley.com/doi/10.1111/cup.13027
Banta, J., Beasley, K., Kobayashi, T., & Rohena, L. (2016). Encephalocraniocutaneous lipomatosis (Haberland syndrome): A mild case with bilateral cutaneous and ocular involvement. JAAD case reports, 2(2), 150–152. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867906/
Patterson, A. T., Beasley, K. J., & Kobayashi, T. T. (2016). Fibroelastolytic papulosis: histopathologic confirmation of disease spectrum variants in a single case. Journal of cutaneous pathology, 43(2), 142–147. https://onlinelibrary.wiley.com/doi/10.1111/cup.12569
Beasley, K., Panach, K., & Dominguez, A. R. (2016). Disseminated Candida tropicalis presenting with Ecthyma-Gangrenosum-like Lesions. Dermatology online journal, 22(1), 13030/qt7vg4n68j. https://pubmed.ncbi.nlm.nih.gov/26990472/
Kimes, K., Beasley, K., & Dalton, S. R. (2015). Eruptive milia and comedones during treatment with dovitinib. Dermatology online journal, 21(9), 13030/qt8kw141mb. https://pubmed.ncbi.nlm.nih.gov/26437285/
Miladi, A., Thomas, B. C., Beasley, K., & Meyerle, J. (2015). Angioimmunoblastic t-cell lymphoma presenting as purpura fulminans. Cutis, 95(2), 113–115. https://pubmed.ncbi.nlm.nih.gov/25750965/
Beasley K, Dai JM, Brown P, Lenz B, Hivnor CM. (2013). Ablative Fractional Versus Nonablative Fractional Lasers – Where Are We and How Do We Compare Differing Products?. Curr Dermatol Rep, 2, 135–143. https://idp.springer.com/authorize?response_type=cookie&client_id=springerlink&redirect_uri=https%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs13671-013-0043-0
Siami P, Beasley K, Woolen S, Zahn J. (2012). A retrospective study evaluating the efficacy and tolerability of intra-abdominal once-yearly histrelin acetate subcutaneous implant in patients with advanced prostate cancer. UroToday Int J, June 5(3), art 26. https://www.urotoday.com/volume-5-2012/vol-5-issue-3/51132-a-retrospective-study-evaluating-the-efficacy-and-tolerability-of-intra-abdominal-once-yearly-histrelin-acetate-subcutaneous-implants-in-patients-with-advanced-prostate-cancer.html
Siami P, Beasley K. (2012). Dutasteride with As-Needed Tamsulosin in Men at Risk of Benign Prostate Hypertrophy Progression. UroToday Int J, Feb 5(1), art 93. https://www.urotoday.com/volume-5-2012/vol-5-issue-1/48691-dutasteride-with-as-needed-tamsulosin-in-men-at-risk-of-benign-prostatic-hypertrophy-progression.html