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Testone CIK

Testone CIK is a compounded medication prepared by specialized pharmacies and used to treat men with low testosterone due to certain medical conditions.

Medical Review byMike Bohl, MD, MBA, MPH, MS, ALMUpdated May 20, 2025

Medication Name

Testone CIK

*image for illustrative purpose only

Testone CIK

*image for illustrative purpose only

Basics

Testone CIK (testosterone cypionate) is a compounded testosterone replacement therapy (TRT) medication often used to treat men with hypogonadism, a condition characterized by low testosterone levels. As a compounded formulation, Testone CIK is typically prepared by specialized pharmacies and may contain a combination of testosterone and other ingredients designed to optimize absorption and effectiveness. It is given as an injection.

Like other TRT options, it is intended to help alleviate symptoms of low testosterone, including fatigue, decreased libido, muscle loss, and mood disturbances. However, because it is a compounded medication, it is not approved by the United States Food and Drug Administration (FDA). This lack of approval means the medication’s efficacy and safety isn’t established and may vary between formulations and compounding pharmacies. 

Men considering taking Testone CIK should consult a healthcare provider to determine whether it is a suitable and safe option for their testosterone replacement needs. While taking this medication, regular medical monitoring is essential to ensure appropriate dosing and to mitigate adverse effects.

*Testone CIK Approved Uses

Testone CIK (testosterone cypionate) is not an FDA-approved drug

*Testone CIK Drug Category

Androgen

*Testone CIK Side Effects

The following adverse reactions in the male have occurred with some androgens:

  • Endocrine and urogenital: Breast tissue development in males and excessive frequency and duration of penile erections. Oligospermia may occur at high dosages

  • Skin and appendages: Hirsutism, male pattern of baldness, seborrhea, and acne

  • Cardiovascular disorders: heart attack, stroke

  • Fluid and electrolyte disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates

  • Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis

  • Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia

  • Nervous system: Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia

  • Allergic: Hypersensitivity, including skin manifestations and anaphylactoid reactions

  • Vascular disorders: Venous thromboembolism

  • Special senses: Rare cases of central serous chorioretinopathy (CSCR)

  • Miscellaneous: Inflammation and pain at the site of intramuscular injection

Testone CIK Cost

The cost of Testone CIK varies depending on where you buy it and your insurance plan. Without insurance, it may cost between $112 and $137 per 200-milligram (mg) dose. Insurance may cover all or some of the cost of this medication, though many insurance companies and plans only provide limited coverage, if any, for compounded medications.

How To Get Testone CIK

Testone CIK is only available by prescription from a healthcare provider. If you’re interested in taking this medication, make an appointment with your provider. They can assess your testosterone levels and discuss whether testosterone therapy is the right treatment for you based on factors like your health status, medical history, and symptoms.

*Interactions & Contraindications

  • Known hypersensitivity to the drug

  • Males with carcinoma of the breast

  • Males with known or suspected carcinoma of the prostate gland

  • Women who are pregnant

  • Patients with serious cardiac, hepatic or renal disease

  • Drug interactions: Androgens may increase sensitivity to oral anticoagulants, concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone, in diabetic patients the metabolic effects of androgens may decrease blood glucose and insulin requirements

*Warnings & Precautions

  • Patients with benign prostatic hypertrophy may develop acute urethral obstruction

  • Priapism or excessive sexual stimulation may develop

  • Oligospermia may occur after prolonged administration or excessive dosage

  • Testosterone cypionate should not be used interchangeably with testosterone propionate because of differences in duration of action

  • Testosterone cypionate is not for intravenous use

  • Patients should be instructed to report any of the following: nausea, vomiting, changes in skin color, ankle swelling, too frequent or persistent erections of the penis

  • Hemoglobin and hematocrit levels (to detect polycythemia) should be checked periodically in patients receiving long-term androgen administration

  • Serum cholesterol may increase during androgen therapy

  • Androgens may decrease levels of thyroxine-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4

  • High blood calcium may occur in immobilized patients

  • Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking

  • There have been postmarketing reports of venous thromboembolic events, including deep vein thrombosis (DVT) and pulmonary embolism (PE), in patients using testosterone products, such as testosterone cypionate

  • Long term clinical safety trials have not been conducted to assess the cardiovascular outcomes of testosterone replacement therapy in men

  • Testosterone has been subject to abuse, typically at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids

  • Edema, with or without congestive heart failure, may be a serious complication in patients with pre-existing cardiac, renal or hepatic disease

  • Breast tissue development in males may develop and occasionally persists in patients being treated for hypogonadism

  • The preservative benzyl alcohol has been associated with serious adverse events, including the "gasping syndrome", and death in pediatric patients

  • Androgen therapy should be used cautiously in healthy males with delayed puberty

  • This drug has not been shown to be safe and effective for the enhancement of athletic performance

  • Pregnancy: The use of testosterone in women who are pregnant is contraindicated

  • Breastfeeding: Testosterone cypionate is not recommended for use in nursing mothers

Testone CIK Alternatives

There are other treatments available for low testosterone or hypogonadism. Some treatments may be better suited to you than others. If you’re interested in an alternative to Testone CIK, consider connecting with a healthcare provider who can help you evaluate your options.

Other types of testosterone replacement therapy (sometimes called androgen replacement) include:

  • Injectable testosterone medications, such as Aveed® or Depo®-Testosterone

  • Implantable testosterone pellets, such as Testopel®

  • Oral testosterone therapy medications such as Jatenzo® and Tlando®

  • Topical testosterone, such as Androderm® (testosterone patch) and Testim® (testosterone gel)

Alternatives to TRT that may help manage low testosterone in men include the following options, all of which can signal the body to have or make more testosterone:

  • Aromatase inhibitors like Arimidex® (anastrozole)

  • Human chorionic gonadotropin (hCG) or Ovidrel®, a lab-made version of hCG

  • Selective estrogen receptor modulators like Clomid® (clomiphene)

Your healthcare provider may also prescribe lifestyle shifts as non-medication alternatives, as they can support healthy testosterone levels. Some examples may include:

  • Regular exercise

  • Stress management

  • Dietary improvements

  • Getting enough sleep

  • Weight loss

FAQs

Testone CIK contains the active ingredient testosterone cypionate, which is an androgen. An androgen is a sex hormone that helps develop and maintain certain male characteristics including fertility and sexual function. 

Testone CIK’s active ingredient, testosterone cypionate, is recommended to be given at a dosage of 50 to 400 mg every two to four weeks. A healthcare provider can determine the best dosage for you.

Testosterone cypionate is administered via deep gluteal intramuscular injection. 

It’s not known if testosterone cypionate injections can safely or effectively treat men who have low testosterone due to aging.

References

*This information is from the label for brand name Testone CIK®. See the Full Prescribing Information for more complete information. Testosterone cypionate, the active ingredient in Testone CIK, may also be the active ingredient in other medications, and this information may not be accurate for all medications that include the active ingredient testosterone cypionate.

  1. Edwards RZ, et al. (2020). Improving low testosterone naturally. https://www.va.gov/WHOLEHEALTHLIBRARY/docs/Improving-Low-Testosterone-Naturally.pdf 

  2. Handelsman DJ, et al. (2020). Androgen physiology, pharmacology, use and misuse. https://www.ncbi.nlm.nih.gov/books/NBK279000/ 

  3. Ide V, et al. (2021). Treatment of men with central hypogonadism: alternatives for testosterone replacement therapy. https://www.mdpi.com/1422-0067/22/1/21 

  4. Sizar O, et al. (2023). Androgen replacement. https://www.ncbi.nlm.nih.gov/books/NBK534853/ 

  5. US Food & Drug Administration. (2022). Testosterone cypionate injection label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/216318s000lbl.pdf 

  6. WellRx. (n.d.). Testone CIK: Prices, uses, and interactions. https://www.wellrx.com/prescriptions/testone-cik/

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