Enclomiphene Price Guide: Average Costs and Alternatives

Key Takeaways:

• Enclomiphene typically costs $50–$150 per month if you pay out of pocket. Hims offers predictable subscription plans for enclomiphene starting at $99 per month.

• Location, insurance coverage, eligibility requirements, and formulation or dosing strength can all influence the final price of enclomiphene.

• Enclomiphene is a drug that supports natural hormone health by boosting the body’s own production of testosterone while protecting fertility — making it an appealing alternative to traditional testosterone replacement therapy (TRT). It’s not FDA-approved, and more research is needed to study both its side effects and the implications of long-term use.
  

The cost of enclomiphene citrate can vary depending on several factors — including your location, dose, whether you pay out of pocket, and if you use a subscription plan. Enclomiphene is a compounded medication, and it isn’t FDA-approved. Insurance coverage varies by plan, though many providers do not cover compounded medications, meaning many users pay for enclomiphine directly.

Since enclomiphene is only available through compounding pharmacies with a valid prescription, access to the drug can be limited. As a first step to getting enclomiphene, you might consider using a telehealth platform like Hims to test for low testosterone at home. Next, a provider on the Hims platform may prescribe enclomiphene following a medical consultation.

Below, we’ll break down the price of enclomiphene, the factors that influence its cost, and how to determine if it’s ultimately the right treatment option for you.

Though testosterone replacement therapy (TRT) has long been the standard treatment for low testosterone, there may be a new player in the game. Newer studies are suggesting that enclomiphene can be just as effective, and — as opposed to TRT — it offers the bonus of not compromising a man’s fertility profile.

Enclomiphene belongs to a class of drugs called selective estrogen receptor modulators (SERMs). By blocking estrogen’s feedback on the hypothalamus, enclomiphene triggers the pituitary gland to release more luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones tell the testes to increase both testosterone and sperm production, supporting natural hormone balance while protecting fertility.

TRT works differently: It supplies the body with synthetic testosterone, often shutting down natural testosterone production. As a result, TRT can lower sperm count and increase the risk of infertility — a side effect that enclomiphene may help to avoid. Unlike anabolic steroids, which also introduce synthetic hormones and can disrupt long-term hormone health, enclomiphene works to restore your body’s natural production of testosterone.

Enclomiphene pricing can vary considerably, typically ranging from $50 to $150 per month for an uninsured patient, depending on dose, the prescribing pharmacy, and whether the medication is compounded locally. Keep in mind that billing for lab testing and office visits is often separate and can add hundreds of dollars per year to overall treatment costs.

Membership plans for enclomiphene through Hims start at $99 per month for a 10-month plan. This price includes the medication, discreet shipping, and ongoing provider monitoring, so you’re not paying piecemeal for multiple services. But there are other subscription plans to consider. Here are all the enclomiphene price options through Hims:

• Initial lab kit: $94

• 3-month plan: $199/month

• 5-month plan: $139/month

• 10-month plan $99/month

Enclomiphene is a compounded and not approved by the Food and Drug Administration (FDA), which means it may not be covered by insurance. However, coverage may vary by plan, so it’s best to contact your carrier to figure out the details.

Even if your plan does cover enclomiphene, you may need to provide documentation of medical necessity (like blood work showing low testosterone levels or clinical hypogonadism) and still be responsible for other out-of-pocket expenses, like copays, deductibles, or follow-up lab tests.

Various factors may influence the price of enclomiphene, such as:

• Location. Where you purchase your medication can make a difference in the cost.

• Insurance. Insurance plans have different policies about what they cover, how much of it they cover, and for how long. Since enclomiphene is compounded and not FDA-approved, some plans may not cover it, leaving the user to pay out of pocket.

• Eligibility and diagnosis. To receive an enclomiphene prescription, you must meet medical criteria such as documented low testosterone. The testing and consultations required to confirm eligibility can add to your overall costs.

• Formulation and dose strength. Because enclomiphene is compounded, pricing depends on the pharmacy, the formulation, and the dosing schedule your provider prescribes. Higher doses or longer treatment courses may cost more.

Enclomiphene can be less expensive than certain TRT formulations, including testosterone gels, creams, and pellets. These topical and implantable therapies often cost several hundred dollars per month or more without insurance, while enclomiphene from a compounding pharmacy or telehealth provider may fall closer to the $50-$150 range. Testosterone injections tend to be the least expensive option among TRT formulations, and pellets are the most costly.

It’s also important to note that insurance may be more likely to cover TRT because it’s an FDA-approved treatment for low testosterone. That means your out-of-pocket cost could be lower for TRT if you have comprehensive insurance coverage. However, for those paying cash, enclomiphene can be the more predictable and accessible option, especially on subscription plans, like those Hims offers, that bundle medication with ongoing medical support.

To access enclomiphene, you’ll need a prescription from a licensed healthcare professional after a medical consultation. This typically involves blood work to confirm low testosterone levels and ensure that enclomiphene is the right fit for you.

Traditionally, enclomiphene has only been available through compounding pharmacies with a prescription, which can make access feel limited or inconsistent. Hims streamlines that process by offering online medical consultations, at-home testing, and convenient prescription delivery.

Hims offers access to several testosterone treatments, including prescription enclomiphene and a combination therapy of enclomiphene + tadalafil (the active ingredient in Cialis^®) to address both low testosterone and erectile dysfunction — a common symptom of low T.

Bundled pricing starts at $99 per month for 10 months and includes the consultation, medication, delivery, and ongoing provider support for treatment adjustments as needed. The initial lab kit costs $94.

Studies support that enclomiphene is well-tolerated with few adverse effects, though more rigorous, large-scale clinical trials are needed to understand the drug’s long-term safety and effectiveness.

Clinical trials have shown that enclomiphene can cause side effects in some users, including headaches, nausea, hot flashes, and elevated estradiol levels (a form of estrogen). The medication may also not be suitable for those with a history of blood clots and cardiac disorders, as enclomiphene may increase the risk of these events.

Though the FDA doesn’t approve or verify compounded drugs for safety, effectiveness, or quality, it’s worth noting that enclomiphene is one of the isomers in the medication clomiphene citrate (Clomid^®), which is FDA-approved for infertility in women. Like enclomiphene, clomiphene is also sometimes prescribed off-label to men with low testosterone. However, research comparing enclomiphene to clomiphene has shown that while both treatments may improve testosterone levels, enclomiphene has a lower rate of side effects, such as mood swings and male breast growth (gynecomastia). Zuclomiphene, clomiphene’s other isomer, is responsible for these estrogenic side effects.

Read more about enclomiphene’s safety and side effects.

Enclomiphene is emerging as a practical, fertility-safe option for men with low testosterone, but the cost can depend on factors like your location, insurance plan, and dose. Unlike TRT, enclomiphene stimulates your body’s own production of testosterone, helping restore hormone balance without compromising sperm health.

Through Hims, accessing enclomiphene is predictable and straightforward, with bundled pricing, at-home lab testing, and ongoing support. Cost is just one piece of the decision for men weighing the potential benefits of enclomiphene. Talk with your provider to decide if enclomiphene is the right fit for your long-term hormone health.

Is there a generic version of enclomiphene?

No, enclomiphene itself is a compounded medication, and no brand-name version of the medication is sold in the U.S.

Is enclomiphene FDA-approved?

No enclomiphene is not FDA-approved, but clomiphene, which contains enclomiphene, is FDA-approved for female infertility.

Can I use my HSA or FSA for enclomiphene?

Sometimes, but it depends on your provider and plan. Hims doesn’t currently accept HSA or FSA payments for enclomiphene.

How long do I need to take enclomiphene?

Many men need ongoing treatment to maintain hormone levels.

Does enclomiphene preserve fertility?

Yes, unlike TRT, enclomiphene stimulates spermatogenesis instead of suppressing it.

Is enclomiphene safe for men without low T?

No, enclomiphene is only intended for men with clinically low testosterone, as prescribed by a healthcare provider.

Who shouldn’t take enclomiphene?

Enclomiphene only works for men with secondary hypogonadism, which is when the brain isn’t signaling the testes to make testosterone. Enclomiphene isn’t effective for primary hypogonadism (testicular failure), and it’s not meant for men with normal testosterone levels, athletes looking for performance gains, or those with certain health risks like a history of blood clots.