Liver health is the overall condition and function of the liver, the organ that filters toxins, processes nutrients, and keeps countless systems running smoothly. A healthy liver is essential for energy balance, immune support, and overall wellness.
Your liver works nonstop to keep your body in balance. When the liver isn’t functioning properly (for example, due to liver disease or cirrhosis), its ability to clear waste products is reduced. This can lead to accumulation of metabolic byproducts and may cause symptoms like fatigue and abdominal discomfort, as well as complications such as jaundice or hepatic encephalopathy.
Many liver conditions progress quietly with few symptoms until significant damage has occurred. That’s why routine monitoring through blood tests can provide early insights into your liver’s function and overall health. Keeping your liver healthy also supports other systems, including your metabolism, immune defense, and cardiovascular health, since the liver regulates fats, sugars, and inflammatory processes that affect the entire body.
Lab testing through Hims is built around key biomarkers that reflect how your body is performing across major health systems. Each test focuses on high-impact indicators chosen to give you the clearest picture of your well-being and where to take action next. Instead of testing everything, Hims zeroes in on the markers that matter most for guiding long-term health improvements.
Tests for liver health can help assess how well your liver is working by measuring key proteins, enzymes, and waste products. Together, these biomarkers offer a picture of your liver’s function, nutrition status, and possible injury.
Alanine Transaminase (ALT)
Alanine transaminase (ALT) is an enzyme found in liver cells that helps process amino acids. This enzyme is a key marker that shows if your liver cells are healthy and working normally.
Aspartate Aminotransferase (AST)
Aspartate aminotransferase (AST) is an enzyme in the liver and muscles that helps to process amino acids. Healthy levels mean your liver and muscles are not under stress or injured.
Alkaline Phosphatase (ALP)
Alkaline phosphatase (ALP) is an enzyme that reflects bile flow and liver function. A healthy level indicates proper bone metabolism and that your liver and gallbladder are functioning without signs of stress.
Albumin
Albumin is a protein made by the liver that helps carry hormones, vitamins, and nutrients through the blood. It also helps to keep fluid in your blood vessels.
Total Bilirubin
Bilirubin is a waste product made when old red blood cells break down. Your liver helps remove bilirubin from your blood, so normal levels usually mean your liver is clearing waste efficiently.
Total Protein
Total protein measures the combined levels of albumin and globulin proteins that support fluid balance, hormone and drug transport, and the immune system. Healthy levels mean that your body is currently maintaining a good balance of these important proteins.
Globulin
Globulins are a group of proteins in your blood that include antibodies, which help your body fight infection, and other proteins that carry hormones and nutrients. Healthy levels suggest your immune system and liver are working well.
De Ritis Ratio
This ratio compares aspartate aminotransferase (AST) to alanine transaminase (ALT), two enzymes released when liver or muscle cells are stressed. A normal ratio suggests your liver is functioning well and not showing signs of chronic damage or stress.
With lab testing through Hims, you get clear results that span multiple areas of health — connecting the dots between your cardiovascular system, metabolism, hormones, liver, kidneys, nutrients, inflammation, immune function, blood health, stress, and even biological age. The results are explained clearly and simply, so you can easily understand what’s happening inside your body.
Beyond the numbers, Hims provides actionable insights into where you need to focus to improve your health. Each result comes with insights to help you make sense of your biomarkers and identify practical steps to support better outcomes.
If your results suggest areas for improvement, you’ll receive an action plan designed by experts that includes lifestyle guidance and, when deemed appropriate by a healthcare provider, prescription medication to help you reach your goals.
More than 2.4 million people trust Hims & Hers for accessible, science-backed care — from lab testing to ongoing health management.1
Who should get tested for liver health and when?
Liver health testing may be helpful if you:
• Have risk factors for liver disease, such as heavy alcohol use, obesity, type 2 diabetes, or a family history of liver disease — all of which are major causes of liver damage in the U.S.
• Take medications or supplements that can affect the liver.
• Experience symptoms like fatigue, unexplained weight changes, and abdominal discomfort. If you notice any of these, see a healthcare provider and seek prompt medical attention if you develop jaundice (yellowing of the skin or eyes), as it may indicate a serious liver or bile duct problem.
Routine liver function tests are often included in annual health panels. However, your healthcare provider may suggest more frequent monitoring if you have risk factors or other chronic conditions
Can I improve my liver health through lifestyle changes?
Yes. Healthy lifestyle changes like limiting alcohol, eating a balanced diet, maintaining a healthy weight, and exercising regularly can all support liver function. However, lifestyle changes may not reverse advanced damage once it has occurred.
Do abnormal liver biomarkers always mean I have liver disease?
Not always. Liver enzymes can fluctuate due to temporary issues like infections or medications. Persistent or significantly abnormal results, however, should be evaluated by a healthcare provider.
What’s the difference between ALT and AST?
Both are enzymes released when liver cells are damaged. ALT mainly comes from the liver, while AST is also found in muscles and the heart, so its levels can rise from non-liver causes.
Can supplements harm the liver?
Yes. Some herbal or over-the-counter supplements can cause liver injury. It’s best to talk with a healthcare provider before starting new supplements.
Find your baseline with 120 biomarker tests, then plan for your health breakthrough.
Reviewed by Felix Gussone, MD
Published 11/13/2025
