Hormone Health

Hormone health is the balance of the body’s chemical messengers, including testosterone, cortisol, and thyroid hormones. These messengers help regulate mood, metabolism, energy, muscle strength, and sexual function. When levels are stable, the body tends to feel and perform at its best. When they’re imbalanced, they can affect sleep, stress, energy, and sexual health.

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Why Hormone Health Matters

Hormone imbalances affect nearly every system in the body and can contribute to fatigue, weight changes, infertility, low libido, and mood shifts. They are also linked to long-term conditions like diabetes and thyroid disease. 

Testing key hormones can help uncover patterns that point to possible imbalances. While lab tests don’t diagnose conditions on their own, they can help you and your healthcare provider determine whether further evaluation is needed.

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Biomarkers We Track For Your Hormone Health

Lab testing through Hims is built around key biomarkers that reflect how your body is performing across major health systems. Each test focuses on high-impact indicators chosen to give you the clearest picture of your well-being and where to take action next. Instead of testing everything, Hims zeroes in on the markers that matter most for guiding long-term health improvements.

Hormone health testing through Hims looks at levels of reproductive, thyroid, growth, and stress-related hormones. Together, they provide a snapshot of how your endocrine system is working.

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Insulin-like Growth Factor 1 ( IGF-1) Advanced plan

Insulin-like growth factor 1 (IGF-1) reflects your body's growth hormone activity. A healthy level means your body has what it needs to support your muscle, bone, and tissue health.

IGF-1 Z-score Advanced plan

Insulin-like growth factor 1 (IGF-1) reflects your body's growth hormone activity. Because IGF-1 levels vary significantly with age, sex, and pubertal stage, a z-score is important in indicating how your IGF-1 level compares to other men in your age group, measured in standard deviations. 

Estradiol

Estradiol is a form of estrogen that men make from testosterone. At a healthy level, it supports bone strength, libido, brain function, and heart health.

Follicle Stimulating Hormone (FSH)

Follicle-stimulating hormone (FSH) is a hormone produced by a part of your brain called the pituitary. It is essential for sperm production and reproductive function. 

Luteinizing Hormone (LH)

Luteinizing hormone (LH) is produced by a part of your brain called the pituitary. It is a crucial hormone that stimulates testosterone production in the testicles. 

Prostate Specific Antigen (PSA)

Prostate-specific antigen (PSA) is a protein produced by the prostate gland that is used for prostate cancer screening. A healthy level suggests that the prostate is functioning optimally.

Sex Hormone Binding Globulin (SHBG)

Sex hormone-binding globulin (SHBG) is a protein that carries testosterone and estrogen in the bloodstream. Unlike some other carrier proteins, it holds on to testosterone and estrogen very tightly, making them less available for your body to use.

Free Testosterone

Free testosterone is the part of your total testosterone that your body can use immediately to support daily energy, libido, and muscle performance. It’s also a key marker of overall vitality. A healthy, balanced level means your body has what it needs to function at its best.

Total Testosterone

Total testosterone is a measurement of all of the testosterone in your bloodstream. It counts all forms of the hormone in your blood, including free molecules and those attached to proteins like albumin and SHBG. This measurement is the go-to to determine if someone has a testosterone deficiency.

Why Get Labs Through Hims

With lab testing through Hims, you get clear results that span multiple areas of health — connecting the dots between your cardiovascular system, metabolism, hormones, liver, kidneys, nutrients, inflammation, immune function, blood health, stress, and even biological age. The results are explained clearly and simply, so you can easily understand what’s happening inside your body.

Beyond the numbers, Hims provides actionable insights into where you need to focus to improve your health. Each result comes with insights to help you make sense of your biomarkers and identify practical steps to support better outcomes.

If your results suggest areas for improvement, you’ll receive an action plan designed by experts that includes lifestyle guidance and, when deemed appropriate by a healthcare provider, prescription medication to help you reach your goals.

More than 2.4 million people trust Hims & Hers for accessible, science-backed care — from lab testing to ongoing health management.1

The Labs difference

This information is not medical advice and lab results alone are not intended to diagnose, treat, or cure any condition. A provider will reach out about critical results and plans include access to 24/7 provider messaging.

1 As of June 30, 2025

Related Health Categories

Heart Health

Low testosterone can contribute to higher cholesterol and blood pressure, while excess levels may put additional strain on the cardiovascular system.

Blood Health

Testosterone helps stimulate red blood cell production, so low levels can lead to anemia.

Thyroid Health

Thyroid hormones regulate metabolism and energy, and interact with sex hormones. Thyroid dysfunction can affect testosterone levels and fertility.

Nutrients

A decline in testosterone can gradually weaken bone density over time.

Metabolic Health

Hormones like insulin affect weight, blood sugar, and energy, which are connected to reproductive hormones.

Inflammation & Stress

Stress hormones like cortisol can disrupt reproductive hormones.

Immune Defense

Because testosterone has mild immunosuppressive effects, it may lower susceptibility to autoimmune conditions while increasing vulnerability to certain infections.

Frequently Asked Questions

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Who should get tested for hormone health and when?

Hormone testing may be helpful if you are experiencing:

• Persistent fatigue or low energy

• Changes in weight, hair, or skin

• Low libido or sexual dysfunction

• Difficulty with fertility

• Symptoms of thyroid imbalance, like unexplained weight changes, temperature sensitivity, or mood shifts

Guidelines recommend that certain groups discuss routine testing with their healthcare providers. For example, healthcare providers should offer prostate cancer screening every two to four years for individuals between 50 and 69 years of age. The frequency depends on your health history, age, and symptoms.

Can lifestyle changes improve hormone balance?

Yes. Nutrition, sleep, exercise, and stress management can all help support hormone health, although some hormone conditions require medical treatment.

What’s the difference between total and free testosterone?

Total testosterone measures all testosterone in the blood. Free testosterone measures the portion available for the body to use, often giving more insight into symptoms.

Do hormone levels naturally change with age?

Yes. Testosterone gradually decreases in men with age.

Should everyone get hormone testing?

Not always. Testing is most helpful if you have symptoms or are monitoring age-related changes. Routine hormone screening isn’t recommended for everyone.

Is hormone testing only for fertility concerns?

No. While fertility is one reason, hormone testing can also help with issues like low energy, weight changes, or shifts in sexual health.

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Sources & References

  1. American Cancer Society. (2023). American Cancer Society Recommendations for Prostate Cancer Early Detection. https://www.cancer.org/cancer/types/prostate-cancer/detection-diagnosis-staging/acs-recommendations.html 

  2. Association for Diagnostics & Laboratory Medicine. (2023). Estradiol Testing in Men. https://myadlm.org/advocacy-and-outreach/optimal-testing-guide-to-lab-test-utilization/a-f/estradiol-testing-in-men 

  3. Dandona P, et al. (2010). A practical guide to male hypogonadism in the primary care setting. https://pmc.ncbi.nlm.nih.gov/articles/PMC2948422/ 

  4. Guzelce EZ, et al. (2022). Accurate measurement of total and free testosterone levels for the diagnosis of androgen disorders. https://www.sciencedirect.com/science/article/pii/S1521690X22000707 

  5. Hammond GE, et al. (2012). Evolving utility of sex hormone-binding globulin measurements in clinical medicine. https://pubmed.ncbi.nlm.nih.gov/22531107  

  6. Health Alterations. (2024). Endocrine Alterations.  https://www.ncbi.nlm.nih.gov/books/NBK613062/ 

  7. Jia LI, et al. (2003). Androgen Receptor Activity at the Prostate Specific Antigen Locus: Steroidal and Non-Steroidal Mechanisms. https://aacrjournals.org/mcr/article/1/5/385/232263/Androgen-Receptor-Activity-at-the-Prostate

Reviewed by Felix Gussone, MD

Published 11/13/2025