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Best Face Cream For Wrinkles

Angela Sheddan

Reviewed by Angela Sheddan, DNP, FNP-BC

Written by Our Editorial Team

Published 03/18/2021

Updated 03/19/2021

Even though you need very little reminding, but always there to point out how quickly life is passing by, are a number of lines and creases spread across your face.

Facial wrinkles are an expected part of the aging process - right up there with grey hairs and a sudden appreciation for early bedtimes.

However, while expected, wrinkles may not always be welcome, which is where anti-aging products such as face creams come in.

We're picking out the best anti-aging ingredients to look out for in your face creams. We'll also be explaining what makes each ingredient so great at its job. But first, let's check out the different kinds of wrinkles that may line up your face.

Types of Wrinkles

Wrinkles are divided into two types

  • Static

  • Dynamic

Wrinkles are  static where they remain no matter what funny face or another movement your facial muscles are pulling. Wrinkles are dynamic when they are formed by the continuous movements we make such as squinting, smiling, and another which you're probably doing at this very moment — furrowing your brows.

Now that the targets have been spotted, here are the best ingredients to help with reducing their appearance.

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Best Skincare Ingredients for Face Creams

Because wrinkles are formed when your skin loses moisture and elasticity over time, you're going to want products that can infuse your skin with both properties for younger-looking skin.

You're also going to want something that can protect you from sun damage, 

These include:

Hydroxy acids

These are also known as fruit acids and they consist of alpha hydroxy acid (AHA) and beta hydroxy acid (BHAs). These are top-tier products to help with reducing the appearance of wrinkles.

Alpha hydroxy acids

These compounds take their roles as anti-aging ingredients more than a little seriously. They work on both the outer and inner layers of the skin.

Once applied, AHAs exfoliate the old and tired skin cells of the epidermis (outer layer). This helps with the production of newer, younger-looking skin cells.

AHAs help to produce softer, smoother skin. They are a big help in lightening age spots and reducing the appearance of wrinkles. But today's star feature is the ability of AHAs to fade wrinkles and lessen the appearance of fine lines.

However, for more anti-aging cool points, AHAs may also help to moisturize and firm up the skin. They are also important for the production of collagen, a protein necessary to give your skin structure.

Beta hydroxy acids

Unlike AHAs which are water-soluble, BHAs — popularly found in salicylic acid are lipid-soluble, making them less irritating to the skin.

However, like glycolic acid, it does a neat job of exfoliating the skin to reveal newer skin cells.  It is also anti-inflammatory, a big plus against inflammation which can cause skin aging. It is also an effective treatment against acne and has been proven to reduce the appearance of facial lines and wrinkles.

Vitamin C

A list of things your skin has to deal with as you age: sun damage, hyperpigmentation, skin sagging, a dull appearance, roughness, and of course, those many wrinkles.

The good news is, vitamin C can help with managing all of these issues. 

While this vitamin helps to reduce the appearance of wrinkles by decreasing wrinkle depth, it can also reduce the effects of photoaging by promoting collagen production. Its antioxidant properties also help to reduce the effects of photoaging. 

Vitamin C may also help to offer protective benefits against UV radiation. To counter skin sagging, it may also help to tighten the skin. To improve or even out skin tone, vitamin C can help to reduce the production of melanin, a pigment that gives the skin color.


Coffee may help to keep you alert while you pretend to work in the mornings, but this isn't its only benefit. Its caffeine content has potent antioxidant benefits which can help to reduce the appearance of aging on your skin.

When it comes to wrinkles, genes and the passage of time may be common causes, but right up there with them is photodamage, courtesy of UVA and UVB sun rays.

Caffeine is a pretty powerful antioxidant. This helps to prevent skin cell death caused by oxidative stress. Its antioxidant properties may not only help to reduce the appearance of wrinkles and fine lines,  but may also control inflammation. These properties may also have anti-cancer benefits.

Hyaluronic acid

If you really want to bring out the big guns against facial wrinkles, look out for face creams containing hyaluronic acid.

This molecule is produced by your body, and is primarily responsible for providing your skin with moisture - around 50 percent of the body's hyaluronic content is contained in the skin. 

However, with the passage of time, smaller amounts of hyaluronic acid are produced in the body, affecting skin moisture which can lead to the formation of wrinkles.

Beyond skin hydration, this molecule also has anti-inflammatory properties. It is also necessary to stimulate collagen production especially following UV exposure. 

Because hyaluronic acid has such potent anti-aging properties, it is a popular ingredient in anti-aging products and has noticeably been featured in injectable fillers. 

You can give your skin a few less wrinkles to worry about by using our Goodnight Wrinkle Men’s Night  Cream, which just so happens to contain caffeine. You can also learn more about hyaluronic acid vs glycolic acid, another popular skincare ingredient.


Tretinoin is a part of the royal family of anti-aging: retinoids. Retinoids are compounds derived from vitamin A and they include retinol, adapalene and others.

Anti-aging face creams that contain tretinoin are looking to benefit from its ability to produce new skin cells. It also has an important role to play in the production of collagen in the body.

But that's not all — tretinoin also improves skin elasticity, an important feature to help with reducing the appearance of wrinkles on your skin. It also improves hydration and has been shown to improve uneven skin tones and rough skin textures.


There's a reason collagen has gotten repeated mention across the ingredients listed, and that's because this protein is a key factor for healthy and healthy-looking skin.

Collagen is produced by the body and it's responsible for giving the skin structure, elasticity and resilience. 

However, as you age, your body produces less and less of this protein, resulting in wrinkles and sagging skin brought on by reduced elasticity.

Supplementing your body's supply of collagen has been shown to improve hydration and elasticity. It has also been shown to reduce the chances of the skin losing water to the environment aka transepidermal water loss. These are needed features to help with really stick it to wrinkles that may appear across the skin.

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Wrapping Up

It doesn't matter what your age or ethnicity is, wrinkles are an inevitable part of the aging process —one you'd be lucky to witness.

However, inevitable or not, wrinkles may not be a favourite facial feature, which is why it's important to get the ingredients right when selecting facial creams to reduce their appearance.

Look out for facial creams containing hyaluronic acid, caffeine, beta hydroxy acids and other listed ingredients for the best results.

To make sure you're using products that are best suited for your skin type, make sure you consult with a dermatologist before making a decision.

13 Sources

  1. American Academy of Facial Esthetics. (n.d.). Types of Wrinkles & Wrinkle Treatments.
  2. Quatresooz, P., Thirion, L., Piérard-Franchimont, C., & Piérard, G. E. (2006). The riddle of genuine skin microrelief and wrinkles. International journal of cosmetic science, 28(6), 389–395. Retrieved from:
  3. Moghimipour E. (2012). Hydroxy Acids, the Most Widely Used Anti-aging Agents. Jundishapur journal of natural pharmaceutical products, 7(1), 9–10. Retrieved from:,epidermal%20and%20the%20dermal%20levels.
  4. Bari, A. U., Iqbal, Z., & Rahman, S. B. (2007). Superficial chemical peeling with salicylic Acid in facial dermatoses. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 17(4), 187–190. Retrieved from:
  5. Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866. Retrieved from:
  6. Rattanawiwatpong, P., Wanitphakdeedecha, R., Bumrungpert, A., & Maiprasert, M. (2020). Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial. Journal of cosmetic dermatology, 19(3), 671–676. Retrieved from:
  7. Li, Y. F., Ouyang, S. H., Tu, L. F., Wang, X., Yuan, W. L., Wang, G. E., Wu, Y. P., Duan, W. J., Yu, H. M., Fang, Z. Z., Kurihara, H., Zhang, Y., & He, R. R. (2018). Caffeine Protects Skin from Oxidative Stress-Induced Senescence through the Activation of Autophagy. Theranostics, 8(20), 5713–5730. Retrieved from:
  8. Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253–258. Retrieved from:
  9. Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-348. Retrieved from:
  10. Babcock, M., Mehta, R. C., & Makino, E. T. (2015). A randomized, double-blind, split-face study comparing the efficacy and tolerability of three retinol-based products vs. three tretinoin-based products in subjects with moderate to severe facial photodamage. Journal of drugs in dermatology JDD, 14(1), 24–30. Retrieved from:
  11. Aguirre-Cruz, G., León-López, A., Cruz-Gómez, V., Jiménez-Alvarado, R., & Aguirre-Álvarez, G. (2020). Collagen Hydrolysates for Skin Protection: Oral Administration and Topical Formulation. Antioxidants (Basel, Switzerland), 9(2), 181. Retrieved from:
  12. Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308–319.
Editorial Standards

Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.

Angela Sheddan, DNP, FNP-BC

Dr. Angela Sheddan has been a Family Nurse Practitioner since 2005, practicing in community, urgent and retail health capacities. She has also worked in an operational capacity as an educator for clinical operations for retail clinics. 

She received her undergraduate degree from the University of Tennessee at Chattanooga, her master’s from the University of Tennessee Health Science Center in Memphis, and her Doctor of Nursing Practice from the University of Alabama in Tuscaloosa. You can find Angela on LinkedIn for more information.

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